umu.sePublications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Metabolic profiles from two different breakfast meals characterized by H-1 NMR-based metabolomics
Show others and affiliations
2017 (English)In: Food Chemistry, ISSN 0308-8146, E-ISSN 1873-7072, Vol. 231, 267-274 p.Article in journal (Refereed) Published
Abstract [en]

It is challenging to measure dietary exposure with techniques that are both accurate and applicable to free-living individuals. We performed a cross-over intervention, with 24 healthy individuals, to capture the acute metabolic response of a cereal breakfast (CB) and an egg and ham breakfast (EHB). Fasting and postprandial urine samples were analyzed using H-1 nuclear magnetic resonance (NMR) spectroscopy and multivariate data analysis. Metabolic profiles were distinguished in relation to ingestion of either CB or EHB. Phosphocreatine/creatine and citrate were identified at higher concentrations after consumption of EHB. Beverage consumption (i.e., tea or coffee) could clearly be seen in the data. 2-furoylglycine and 5-hydroxymethyl-2-furoic acid - potential biomarkers for coffee consumption were identified at higher concentrations in coffee drinkers. Thus H-1 NMR urine metabolomics is applicable in the characterization of acute metabolic fingerprints from meal consumption and in the identification of metabolites that may serve as potential biomarkers.

Place, publisher, year, edition, pages
Elsevier, 2017. Vol. 231, 267-274 p.
Keyword [en]
Metabolomics, Nutrition, H-1 NMR, Urine, Metabolic phenotype, Biomarker
National Category
Nutrition and Dietetics Food Science
Identifiers
URN: urn:nbn:se:umu:diva-136037DOI: 10.1016/j.foodchem.2017.03.142ISI: 000401096500031PubMedID: 28450006OAI: oai:DiVA.org:umu-136037DiVA: diva2:1112980
Available from: 2017-06-21 Created: 2017-06-21 Last updated: 2017-06-21Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full textPubMed

Search in DiVA

By author/editor
Pinto, Rui Climaco
By organisation
Department of Chemistry
In the same journal
Food Chemistry
Nutrition and DieteticsFood Science

Search outside of DiVA

GoogleGoogle Scholar

Altmetric score

Total: 9 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf