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Changes in insulin response in overweight young females and males in relation to other physiological variables after 7 weeks of exercise-training
Umeå University, Faculty of Medicine, Department of Community Medicine and Rehabilitation, Sports medicine.
2017 (English)Independent thesis Basic level (degree of Bachelor), 180 HE creditsStudent thesis
Abstract [en]

Prevention and treatment of type 2 diabetes is of paramount importance as this metabolic disease is a well-established risk factor for cardiovascular diseases, cancer and neurological disorders, all implicated in premature death. The aim of this study was to investigate effects on insulin of exercise training as an intervention. The main question was whether exercise, without dietary changes, would improve insulin sensitivity among young untrained individuals with overweight. The participants completed a seven-week long training period, including pre and post-tests. The major result of the intervention was a decreased insulin response following an oral macronutrient load (ML) seen in 13 of 17 subjects. There was a significant decrease in insulin at 60 minutes after the ML, indicating an improved insulin sensitivity. The analysis of the two subgroups of women and males reveals that the intervention produced a greater reduction in insulin response in women than the males, indicating a gender difference in metabolic adaptation to training. The study also evaluated changes in insulin response after ML compared to changes in other variables and found that changes in body weight, fat mass, visceral fat mass, triglycerides and ApoB correlates positively with change in insulin. This suggests that improvement in lipid metabolism with exercise training is of paramount importance for improved insulin sensitivity.

Place, publisher, year, edition, pages
2017.
Keyword [en]
Insulin, Exercise, Intervention, Overweight, Obesity
National Category
Sport and Fitness Sciences
Identifiers
URN: urn:nbn:se:umu:diva-137070OAI: oai:DiVA.org:umu-137070DiVA: diva2:1115034
External cooperation
Akademiska laboratoriet för klinisk kemi, Uppsala Universitetssjukhus
Educational program
Physical Trainer Pogramme
Available from: 2017-06-26 Created: 2017-06-26 Last updated: 2017-06-26Bibliographically approved

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CiteExportLink to record
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Citation style
  • apa
  • ieee
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Language
  • de-DE
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  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
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Output format
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  • asciidoc
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