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Heart rate variability (HRV) in adolescent females with anxiety disorders and major depressive disorder.
Karolinska Institutet, University of California San Francsisco. (Barn- och Ungdomspsykiatri)ORCID iD: 0000-0001-5790-0518
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2010 (English)In: Acta Paediatrica, ISSN 0803-5253, E-ISSN 1651-2227, Vol. 99, no 4, 604-11 p.Article in journal (Refereed) Published
Abstract [en]

AIM: The aim of this study was to investigate heart rate variability (HRV) in a clinical sample of female adolescents with anxiety disorders (AD) and/or major depressive disorder (MDD) compared with healthy controls and to assess the effect of selective serotonin reuptake inhibitors (SSRI) on HRV.

METHODS: Heart rate variability was measured in adolescent female psychiatric patients with AD and/or MDD (n = 69), mean age 16.8 years (range: 14.5-18.4), from 13 out-patient clinics and in healthy controls (n = 65), mean age 16.5 years (range: 15.9-17.7). HRV was registered in the sitting position during 4 min with no interventions.

RESULTS: Logarithmically transformed high frequency HRV (HF), low frequency HRV (LF) and standard deviation of inter beat intervals (SDNN) were lower in the clinical sample compared with the controls (Cohen's d for HF = 0.57, LF = 0.55, SDNN = 0.60). This was not explained by body mass index, blood pressure or physical activity. Medication with SSRI explained 15.5% of the total variance of HF, 3.0% of LF and 6.5% of SDNN.

CONCLUSIONS: Adolescent female psychiatric patients with AD and/or MDD show reduced HRV compared with healthy controls. Medication with SSRI explained a part of this difference.

Place, publisher, year, edition, pages
2010. Vol. 99, no 4, 604-11 p.
National Category
Clinical Medicine
Identifiers
URN: urn:nbn:se:umu:diva-135790DOI: 10.1111/j.1651-2227.2009.01657.xPubMedID: 20121706OAI: oai:DiVA.org:umu-135790DiVA: diva2:1120530
Available from: 2017-07-06 Created: 2017-07-06 Last updated: 2017-07-06

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CiteExportLink to record
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Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
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  • Other locale
More languages
Output format
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  • asciidoc
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