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The development of an RDoC-based treatment program for adolescent depression: "Training for Awareness, Resilience, and Action" (TARA).
Karolinska Institutet, University of California San Francsisco. (Barn- och Ungdomspsykiatri)ORCID iD: 0000-0001-5790-0518
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2014 (English)In: Frontiers in human neuroscience, Vol. 8, 630Article in journal (Refereed) Published
Abstract [en]

Major depressive disorder (MDD) is one of the current leading causes of disability worldwide. Adolescence is a vulnerable period for the onset of depression, with MDD affecting 8-20% of all youth. Traditional treatment methods have not been sufficiently effective to slow the increasing prevalence of adolescent depression. We therefore propose a new model for the treatment of adolescent depression - Training for Awareness, Resilience, and Action (TARA) - that is based on current understanding of developmental and depression neurobiology. The TARA model is aligned with the Research Domain Criteria (RDoC) of the National Institute of Mental Health. In this article, we first address the relevance of RDoC to adolescent depression. Second, we identify the major RDoC domains of function involved in adolescent depression and organize them in a way that gives priority to domains thought to be driving the psychopathology. Third, we select therapeutic training strategies for TARA based on current scientific evidence of efficacy for the prioritized domains of function in a manner that maximizes time, resources, and feasibility. The TARA model takes into consideration the developmental limitation in top-down cognitive control in adolescence and promotes bottom-up strategies such as vagal afference to decrease limbic hyperactivation and its secondary effects. The program has been informed by mindfulness-based therapy and yoga, as well as modern psychotherapeutic techniques. The treatment program is semi-manualized, progressive, and applied in a module-based approach designed for a group setting that is to be conducted one session per week for 12 weeks. We hope that this work may form the basis for a novel and more effective treatment strategy for adolescent depression, as well as broaden the discussion on how to address this challenge.

Place, publisher, year, edition, pages
2014. Vol. 8, 630
Keyword [en]
RDoC, adolescent depression, attention training, emotion regulation, mindfulness, treatment development, yoga-based movement
National Category
Clinical Medicine
Identifiers
URN: urn:nbn:se:umu:diva-135784DOI: 10.3389/fnhum.2014.00630PubMedID: 25191250OAI: oai:DiVA.org:umu-135784DiVA: diva2:1120536
Available from: 2017-07-06 Created: 2017-07-06 Last updated: 2017-07-06

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CiteExportLink to record
Permanent link

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Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
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  • Other locale
More languages
Output format
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