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Selenium deficiency and selenium supplements: biological effects on fibrosisin chronic diseases, from animal to human studies
School of public Health, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, China.
School of public Health, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, China.
School of public Health, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, China.
School of public Health, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, China.
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2017 (English)In: Handbook of famine, starvation, and nutrient deprivation: from biology to policy / [ed] Preedy V.R., Patel V.B., Springer, 2017, p. 1-20Chapter in book (Refereed)
Abstract [en]

Selenium is a trace element, which is required for normal growth and development of animals and humans. It works by incorporating into proteins to make selenoproteins. These selenoproteins help to prevent free radicals from causing cellular damage, which may in turn lead to the development of various chronic diseases. Selenium deficiency, although is rare, can happen when the body does not have enough selenium. This chapter will review systematically the effects of selenium deficiency on fibrosis in various chronic diseases, such as cardiac fibrosis, liver fibrosis, kidney fibrosis, cystic fibrosis, thyroid fibrosis, oral submucous fibrosis, and pancreatic fibrosis in both animal and human studies. Moreover, their prevention and treatment with selenium supplement will be evaluated as well.

Place, publisher, year, edition, pages
Springer, 2017. p. 1-20
Keywords [en]
Cardiac fibrosis, Cystic fibrosis, Fibrosis, Kidney fibrosis, Liver fibrosis, Oral submucous fibrosis, Selenium deficiency, Selenium supplement, Thyroid fibrosis, Pancreatic fibrosis
National Category
Nutrition and Dietetics Public Health, Global Health, Social Medicine and Epidemiology
Research subject
Food and Nutrition; Pathology
Identifiers
URN: urn:nbn:se:umu:diva-140192DOI: 10.1007/978-3-319-40007-5_67-1ISBN: 978-3-319-40007-5 (print)ISBN: 978-3-319-55386-3 (print)ISBN: 978-3-319-55387-0 (electronic)ISBN: 978-3-319-55388-7 (print)OAI: oai:DiVA.org:umu-140192DiVA, id: diva2:1146530
Available from: 2017-10-03 Created: 2017-10-03 Last updated: 2018-06-09Bibliographically approved

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Qu, Chengjuan

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