umu.sePublications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Smoothelin and intermediate filament proteins in human aortocoronary saphenous vein by-pass grafts.
1999 (English)In: The Histochemical Journal, ISSN 0018-2214, E-ISSN 1573-6865, Vol. 31, no 11, p. 723-7Article in journal (Refereed) Published
Abstract [en]

The aim of this immunohistochemical investigation was to study the distribution of the novel cytoskeletal protein smoothelin and the intermediate filament proteins vimentin and desmin in normal human great saphenous vein and in human aortocoronary by-pass vein grafts. Smoothelin was present in most smooth muscle cells in the media of the native vein. In the neointima of the vein grafts that had been in situ for three months or more, smoothelin was, in general, present only in few smooth muscle cells. Desmin was distributed in the same pattern as smoothelin in the native great saphenous vein. When desmin and smoothelin were present in the neointima, smoothelin was detected in more cells than desmin. Vimentin was present in most cells in all wall layers of both the native saphenous vein and the vein grafts. Vascular smooth muscle cells containing vimentin but not desmin or smoothelin are the principal cells in the neointima of human aortocoronary vein grafts. In some grafts, however, all three cytoskeletal proteins were detected in the neointima. The distribution of smoothelin and desmin in aortocoronary vein grafts support the postulate that these proteins are expressed mainly in the contractile smooth muscle cell phenotype.

Place, publisher, year, edition, pages
1999. Vol. 31, no 11, p. 723-7
National Category
Cell and Molecular Biology
Identifiers
URN: urn:nbn:se:umu:diva-140270PubMedID: 10646837OAI: oai:DiVA.org:umu-140270DiVA, id: diva2:1146776
Available from: 2017-10-04 Created: 2017-10-04 Last updated: 2018-06-09

Open Access in DiVA

No full text in DiVA

PubMed

Authority records BETA

Johansson, B

Search in DiVA

By author/editor
Johansson, B
In the same journal
The Histochemical Journal
Cell and Molecular Biology

Search outside of DiVA

GoogleGoogle Scholar

pubmed
urn-nbn

Altmetric score

pubmed
urn-nbn
Total: 5 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf