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A REGISTER-BASED STUDY OF COGNITIVE FUNCTION AND FUNCTIONAL DISABILITY IN OLD PEOPLE WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD) IN LOW AND MIDDLE-INCOME COUNTRIES.
Umeå University, Faculty of Medicine, Department of Public Health and Clinical Medicine, Epidemiology and Global Health.
2017 (English)Independent thesis Advanced level (degree of Master (One Year)), 10 credits / 15 HE creditsStudent thesis
Abstract [en]

Background: Chronic obstructive pulmonary lung disease (COPD) is increasingly becoming a problem in low and middle-income countries (LMICs) mainly due to an increase in the smoking prevalence and due to an aging population. However, few studies have been done on people with COPD in LMICs. This paper studies the association between cognitive function and functional disability and COPD in people 50 years and older in low and median income countries (LMICs).

Methods: We used data from WHO study on global ageing and adult health (SAGE) wave 1. COPD was defined and categorized in accordance with the Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2017 guideline. Pearson chi square and t-test were used to test the difference between people/cases with and without COPD. Linear regression analysis was used to analyze the association between cognitive function and functional disability with COPD status and COPD stages. Multivariate linear analysis was used to identify predictors of cognitive function and functional disability in individuals with COPD.

Results: The study population consisted of 13586 individuals from five countries. Out of these 4030 had COPD. The mean scores in all test assessing different domain of cognitive function (VR, VF, DSF and DSB) were significantly lower in COPD subjects compared to non-COPD subjects and this was also with overall cognitive score and WHODAS score. There was no significant graded association between COPD GOLD stages and WHODAS score and overall cognitive score. Factors associated with lower cognitive function in COPD subjects were increase in age, female gender, being a current or past smoker, being exposed to indoor pollution and suffering from either stroke or trauma. For functional status increase in age, female gender, smoking in past, dyspnea, exposure to indoor air pollution, having either diabetes, trauma or depression were associated with lower WHODAS score.

Conclusion: Generally, COPD is associated with deterioration of cognitive function and functional status and there is no meaningful difference in cognitive function and functional status across different COPD GOLD stages

Place, publisher, year, edition, pages
2017. , p. 29
Series
Centre for Public Health Report Series, ISSN 1651-341X ; 2017:30
Keywords [en]
Cognitive function, functional disability, chronic obstructive pulmonary disease, COPD
National Category
Public Health, Global Health, Social Medicine and Epidemiology
Identifiers
URN: urn:nbn:se:umu:diva-142703OAI: oai:DiVA.org:umu-142703DiVA, id: diva2:1163851
External cooperation
WHO SAGE - Paul Kowal
Educational program
Master's Programme in Public Health
Presentation
2017-05-23, Room N280, natural Sciences building, Umeå University, Umeå, 09:00 (English)
Supervisors
Examiners
Available from: 2017-12-19 Created: 2017-12-08 Last updated: 2017-12-19Bibliographically approved

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CiteExportLink to record
Permanent link

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Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
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  • asciidoc
  • rtf