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Snus use during the life-course and risk of the metabolic syndrome and its components
Umeå universitet, Medicinska fakulteten, Institutionen för folkhälsa och klinisk medicin, Allmänmedicin.
Umeå universitet, Medicinska fakulteten, Institutionen för folkhälsa och klinisk medicin, Epidemiologi och global hälsa.
Umeå universitet, Medicinska fakulteten, Institutionen för folkhälsa och klinisk medicin, Medicin.
Umeå universitet, Medicinska fakulteten, Institutionen för folkhälsa och klinisk medicin, Näringsforskning.
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2017 (Engelska)Ingår i: Scandinavian Journal of Public Health, ISSN 1403-4948, E-ISSN 1651-1905, Vol. 45, nr 8, s. 733-740Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

Objective: We aimed to investigate the association between life-course exposure to snus and prevalence of the metabolic syndrome and its components in adulthood.

Design and method: Tobacco habits at baseline (age 16) and three follow-ups (ages 21, 30 and 43) were assessed among 880 participants in a population-based cohort in Northern Sweden. Presence of the metabolic syndrome at age 43 was ascertained using the International Diabetes Federation criteria. Odds ratios and CIs for risk of the metabolic syndrome and its components by snus use at 16, 21, 30 and 43 years were calculated using logistic regression. Cumulative snus use was defined as number of life periods (1-4) with current snus use.

Results: At age 43, 164 participants (18.6%) were current snus users. We found no association between exclusive snus use at the ages of 16, 21, 30 and 43 years and the metabolic syndrome at age 43 years. Snus use (among non-smokers) was associated with raised triglycerides and high blood pressure in crude analysis, but not in multivariable models. There was no association between cumulative snus use and risk of the metabolic syndrome. Cumulative snus use was associated with central obesity, raised triglycerides and impaired fasting glucose/diabetes mellitus type 2 in crude analyses, but not after adjustments.

Conclusion: The health consequences of snus exposure from adolescence to mid-adulthood do not seem to include increased risk of the metabolic syndrome or its components. The cardio-metabolic risk of dual exposure to snus and cigarettes may warrant further attention.

Ort, förlag, år, upplaga, sidor
Sage Publications, 2017. Vol. 45, nr 8, s. 733-740
Nyckelord [en]
Swedish moist snuff, hypertension, life-course, metabolic syndrome, metsy, obesity, smokeless tobacco, snus, triglycerides
Nationell ämneskategori
Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi
Identifikatorer
URN: urn:nbn:se:umu:diva-143321DOI: 10.1177/1403494817706631ISI: 000418185200001PubMedID: 28673132OAI: oai:DiVA.org:umu-143321DiVA, id: diva2:1168343
Tillgänglig från: 2017-12-20 Skapad: 2017-12-20 Senast uppdaterad: 2018-06-09Bibliografiskt granskad

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Byhamre, Marja LisaGustafsson, Per E.Jansson, Jan-HåkanWennberg, MariaHammarström, AnneWennberg, Patrik

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Byhamre, Marja LisaGustafsson, Per E.Jansson, Jan-HåkanWennberg, MariaHammarström, AnneWennberg, Patrik
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AllmänmedicinEpidemiologi och global hälsaMedicinNäringsforskning
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Scandinavian Journal of Public Health
Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi

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