umu.sePublications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Comparative genomic analysis of Lactobacillus mucosae LM1 identifies potential niche-specific genes and pathways for gastrointestinal adaptation
Department of Animal Resources Science, Dankook University, Cheonan 31116, Republic of Korea.ORCID iD: 0000-0002-4396-346X
Dankook University.
Dankook University.
Seoul National University.
Show others and affiliations
2017 (English)In: Genomics, ISSN 0888-7543, E-ISSN 1089-8646Article in journal (Refereed) Epub ahead of print
Abstract [en]

Lactobacillus mucosae is currently of interest as putative probiotics due to their metabolic capabilities and ability to colonize host mucosal niches. L. mucosae LM1 has been studied in its functions in cell adhesion and pathogen inhibition, etc. It demonstrated unique abilities to use energy from carbohydrate and non-carbohydrate sources. Due to these functions, we report the first complete genome sequence of an L. mucosae strain, Lmucosae LM1. Analysis of the pan-genome in comparison with closely-related Lactobacillus species identified a complete glycogen metabolism pathway, as well as folate biosynthesis, complementing previous proteomic data on the LM1 strain. It also revealed common and unique niche-adaptation genes among the various L. mucosae strains. The aim of this study was to derive genomic information that would reveal the probable mechanisms underlying the probiotic effect of L. mucosae LM1, and provide a better understanding of the nature of L. mucosae sp.

Place, publisher, year, edition, pages
Elsevier, 2017.
Keywords [en]
Lactobacillus mucosae, Comparative genomics, Probiotics
National Category
Microbiology
Identifiers
URN: urn:nbn:se:umu:diva-145020DOI: 10.1016/j.ygeno.2017.12.009OAI: oai:DiVA.org:umu-145020DiVA, id: diva2:1183455
Available from: 2018-02-16 Created: 2018-02-16 Last updated: 2018-06-09Bibliographically approved

Open Access in DiVA

The full text will be freely available from 2018-12-23 00:00
Available from 2018-12-23 00:00

Other links

Publisher's full text

Authority records BETA

Valeriano, Valerie Diane

Search in DiVA

By author/editor
Valeriano, Valerie Diane
In the same journal
Genomics
Microbiology

Search outside of DiVA

GoogleGoogle Scholar

doi
urn-nbn

Altmetric score

doi
urn-nbn
Total: 51 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf