umu.sePublikationer
Ändra sökning
RefereraExporteraLänk till posten
Permanent länk

Direktlänk
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Annat format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf
Scandinavian SSAI clinical practice guideline on choice of inotropic agent for patients with acute circulatory failure
Umeå universitet, Medicinska fakulteten, Institutionen för kirurgisk och perioperativ vetenskap, Anestesiologi och intensivvård.ORCID-id: 0000-0002-4049-8910
Visa övriga samt affilieringar
2018 (Engelska)Ingår i: Acta Anaesthesiologica Scandinavica, ISSN 0001-5172, E-ISSN 1399-6576, Vol. 62, nr 4, s. 420-450Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

BACKGROUND: Adult critically ill patients often suffer from acute circulatory failure and those with low cardiac output may be treated with inotropic agents. The aim of this Scandinavian Society of Anaesthesiology and Intensive Care Medicine guideline was to present patient-important treatment recommendations on this topic.

METHODS: This guideline was developed according to GRADE. We assessed the following subpopulations of patients with shock: (1) shock in general, (2) septic shock, (3) cardiogenic shock, (4) hypovolemic shock, (5) shock after cardiac surgery, and (6) other types of shock, including vasodilatory shock. We assessed patient-important outcome measures, including mortality and serious adverse reactions.

RESULTS: For all patients, we suggest against the routine use of any inotropic agent, including dobutamine, as compared to placebo/no treatment (very low quality of evidence). For patients with shock in general, and in those with septic and other types of shock, we suggest using dobutamine rather than levosimendan or epinephrine (very low quality of evidence). For patients with cardiogenic shock and in those with shock after cardiac surgery, we suggest using dobutamine rather than milrinone (very low quality of evidence). For the other clinical questions, we refrained from giving any recommendations or suggestions.

CONCLUSIONS: We suggest against the routine use of any inotropic agent in adult patients with shock. If used, we suggest using dobutamine rather than other inotropic agents for the majority of patients, however, the quality of evidence was very low, implying high uncertainty on the balance between the benefits and harms of inotropic agents.

Ort, förlag, år, upplaga, sidor
Hoboken: John Wiley & Sons, 2018. Vol. 62, nr 4, s. 420-450
Nyckelord [en]
low cardiac output, decompensated heart failure, trial sequential analysis, septic shock, cardiogenic shock, levosimendan, dobutamine, surgery, metaanalysis, grade
Nationell ämneskategori
Anestesi och intensivvård
Identifikatorer
URN: urn:nbn:se:umu:diva-145537DOI: 10.1111/aas.13089ISI: 000426998600001PubMedID: 29479665ISBN: 1399-6576 (Electronic) 0001-5172 (Linking) OAI: oai:DiVA.org:umu-145537DiVA, id: diva2:1189024
Tillgänglig från: 2018-03-09 Skapad: 2018-03-09 Senast uppdaterad: 2018-06-09Bibliografiskt granskad

Open Access i DiVA

fulltext(2834 kB)84 nedladdningar
Filinformation
Filnamn FULLTEXT01.pdfFilstorlek 2834 kBChecksumma SHA-512
1df5046b605a52f475569a5ef9868aad7d4c25b481df40e3f0bb77c460434568469627b1d71ac7eb81133d7b952ded4e6cb546718f38216a45d90a84392f99ee
Typ fulltextMimetyp application/pdf

Övriga länkar

Förlagets fulltextPubMed

Personposter BETA

Haney, Michael

Sök vidare i DiVA

Av författaren/redaktören
Haney, Michael
Av organisationen
Anestesiologi och intensivvård
I samma tidskrift
Acta Anaesthesiologica Scandinavica
Anestesi och intensivvård

Sök vidare utanför DiVA

GoogleGoogle Scholar
Totalt: 84 nedladdningar
Antalet nedladdningar är summan av nedladdningar för alla fulltexter. Det kan inkludera t.ex tidigare versioner som nu inte längre är tillgängliga.

doi
pubmed
isbn
urn-nbn

Altmetricpoäng

doi
pubmed
isbn
urn-nbn
Totalt: 149 träffar
RefereraExporteraLänk till posten
Permanent länk

Direktlänk
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Annat format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf