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Shift work, parental cardiovascular disease and myocardial infarction in males
Umeå University, Faculty of Medicine, Department of Public Health and Clinical Medicine, Occupational and Environmental Medicine.
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2018 (English)In: Occupational Medicine, ISSN 0962-7480, E-ISSN 1471-8405, Vol. 68, no 2, p. 120-125Article in journal (Refereed) Published
Abstract [en]

Background: Shift work has been associated with an increased risk of cardiovascular disease (CVD). However, there is a need for more studies to determine whether there is an interaction between shift work and other risk factors of CVD, thereby increasing the risk of CVD in shift workers. Aims: To discern whether shift work and parental mortality from myocardial infarction (MI) or sudden cardiac death (SCD) interact to increase the risk of MI in men. Methods: A case-control dataset was used to assess interaction between shift work and parental history of CVD, using death from MI or SCD, or death before age 65, on an additive scale. Results were reported as relative excess risk due to interaction, attributable proportion due to interaction (AP) and synergy index (SI). Results: There was an interaction between shift work and paternal mortality from MI or SCD, when both factors were present [SI = 2.39; 95% confidence interval (CI) 1.02. 5.6 and AP = 0.4; 95% CI 0.08. 0.73]. Conclusions: Paternal mortality from MI or SCD interacts with shift work to increase the risk of MI in men.

Place, publisher, year, edition, pages
Oxford University Press, 2018. Vol. 68, no 2, p. 120-125
Keywords [en]
Cardiovascular disease, case-control study, heredity, interaction, risk factor
National Category
Occupational Health and Environmental Health
Identifiers
URN: urn:nbn:se:umu:diva-147358DOI: 10.1093/occmed/kqy008ISI: 000429448800010PubMedID: 29444274OAI: oai:DiVA.org:umu-147358DiVA, id: diva2:1204216
Available from: 2018-05-07 Created: 2018-05-07 Last updated: 2018-06-15Bibliographically approved

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Karlsson, B.

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CiteExportLink to record
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Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
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Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf