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Comorbidity of Airway Inflammatory Diseases in Chemical and Building-Related Intolerance
Umeå University, Faculty of Social Sciences, Department of Psychology.
Umeå University, Faculty of Social Sciences, Department of Psychology.
Umeå University, Faculty of Social Sciences, Department of Psychology.
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2018 (English)In: Journal of Occupational and Environmental Medicine, ISSN 1076-2752, E-ISSN 1536-5948, Vol. 60, no 4, p. 295-300Article in journal (Refereed) Published
Abstract [en]

Objectives: This study investigated comorbidity in chemical intolerance (CI) and building- related intolerance (BRI) with (i) chronic sinusitis, chronic obstructive pulmonary disease, allergic and nonallergic asthma and allergic rhinitis, and (ii) airway inflammatory symptoms. Methods: Data from two population-based questionnaire surveys, the Västerbotten and Österbotten Environmental Health Studies, were used. The participants were categorized as CI or BRI and referents, and binary logistic regression analysis was applied. Results: Prevalence rates for the case groups were 7.2% to 40.0% for diseases and 24.3% to 68.9% for symptoms, whereas adjusted odds ratios (ORs) were 3.4 to 26.1 for diseases and 3.3 to 17.0 for symptoms, all being significantly higher than unity. Prevalence rates and ORs were in general higher in BRI than in CI. Conclusion: Inflammatory airway diseases and symptoms are associated with CI and BRI, which encourages further research regarding underlying mechanisms and treatments.

Place, publisher, year, edition, pages
Lippincott Williams & Wilkins, 2018. Vol. 60, no 4, p. 295-300
Keywords [en]
airway inflammation, allergic asthma, allergic rhinitis, building-related intolerance, chemical tolerance, chronic sinusitis, COPD, nonallergic asthma
National Category
Occupational Health and Environmental Health Public Health, Global Health, Social Medicine and Epidemiology
Identifiers
URN: urn:nbn:se:umu:diva-147328DOI: 10.1097/JOM.0000000000001249ISI: 000429441900011PubMedID: 29227362OAI: oai:DiVA.org:umu-147328DiVA, id: diva2:1208697
Available from: 2018-05-18 Created: 2018-05-18 Last updated: 2018-06-09Bibliographically approved

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Claeson, Anna-SaraNordin, Steven

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