umu.sePublications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Haemodialysis with Tinzaparin Versus Dialysate Citrate as Anticoagulation
Umeå University, Faculty of Medicine, Department of Public Health and Clinical Medicine, Cardiology.
Umeå University, Faculty of Medicine, Department of Public Health and Clinical Medicine, Medicine.
2018 (English)In: Blood Purification, ISSN 0253-5068, E-ISSN 1421-9735, Vol. 46, no 3, p. 257-263Article in journal (Refereed) Published
Abstract [en]

Anticoagulation with citrate-containing haemodialysate (cHD) is an alternative to tinzaparin haemodialysate (tHD). The study investigated whether cHD would differ when changed from tHD. The same 18 patients were their own controls followed up with cHD for 5 months. LDL-cholesterol decreased at the end of a cHD session (p = 0.01). Neutrophils (p = 0.013) and monocytes (p = 0.007) dropped more during a cHD session. During the follow-up period of cHD, approximately 50% needed additional tinzaparin. Before the cHD session could start, there was a lower total cholesterol at 2 weeks (p = 0.014) and LDL-cholesterol at 1 month (p = 0.011) versus an increase of LDL at 5 months (p = 0.02). Only patients without additional tinzaparin had a reduction of C-reactive protein (CRP) at 2 months of cHD (p < 0.05) but not later. Solely cHD seems possible only in half of the patients. A greater reduction in granulocytes and monocytes during cHD indicates a more extensive blood membrane interaction, while CRP may be lower.

Place, publisher, year, edition, pages
S. Karger, 2018. Vol. 46, no 3, p. 257-263
Keywords [en]
Biocompatibility, Blood purification, Citrate, Haemodialysis, Haemoglobin, Heparin
National Category
Hematology Cardiac and Cardiovascular Systems
Identifiers
URN: urn:nbn:se:umu:diva-150401DOI: 10.1159/000490409ISI: 000439389800012PubMedID: 29972824Scopus ID: 2-s2.0-85049885888OAI: oai:DiVA.org:umu-150401DiVA, id: diva2:1236853
Available from: 2018-08-06 Created: 2018-08-06 Last updated: 2019-05-21Bibliographically approved

Open Access in DiVA

No full text in DiVA

Other links

Publisher's full textPubMedScopus

Authority records BETA

Mahmood, DanaStegmayr, Bernd

Search in DiVA

By author/editor
Mahmood, DanaStegmayr, Bernd
By organisation
CardiologyMedicine
In the same journal
Blood Purification
HematologyCardiac and Cardiovascular Systems

Search outside of DiVA

GoogleGoogle Scholar

doi
pubmed
urn-nbn

Altmetric score

doi
pubmed
urn-nbn
Total: 70 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf