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Microbiological features distinguishing Lyme disease and relapsing fever spirochetes
Umeå University, Faculty of Medicine, Department of Molecular Biology (Faculty of Medicine). Umeå University, Faculty of Medicine, Molecular Infection Medicine Sweden (MIMS).
Umeå University, Faculty of Medicine, Department of Molecular Biology (Faculty of Medicine). Umeå University, Faculty of Medicine, Molecular Infection Medicine Sweden (MIMS).
2018 (English)In: Wiener Klinische Wochenschrift, ISSN 0043-5325, E-ISSN 1613-7671, Vol. 130, no 15-16, p. 484-490Article in journal (Refereed) Published
Abstract [en]

The recent proposal of splitting the genus Borrelia into two genera in the newly formed family of Borreliaceae, i.aEuro<overline>e. Borrelia and Borreliella has motivated us to reflect upon how these organisms has been characterized and differentiated. This article therefore aims to take a closer look on the biology and virulence attributes of the two suggested genera, i.aEuro<overline>e. those causing Lyme borreliosis and relapsing fever borreliosis. Both genera have much in common with similar infection biological features. They are both characterized as bacterial zoonoses, transmitted by hematophagous arthropods with almost identical microbiological appearance. Nevertheless, a closer look at the genotypic and phenotypic characteristics clearly reveals several differences that might motivate the suggested split. On the other hand, a change of this well-established classification within the genus Borrelia might impose an economical burden as well as a great confusion in society, including medical and scientific societies as well as the general population.

Place, publisher, year, edition, pages
SPRINGER WIEN , 2018. Vol. 130, no 15-16, p. 484-490
Keywords [en]
Borrelia, Borreliella, Lyme borreliosis, Relapsing fever, Taxonomy
National Category
Public Health, Global Health, Social Medicine and Epidemiology
Identifiers
URN: urn:nbn:se:umu:diva-151059DOI: 10.1007/s00508-018-1368-2ISI: 000441195100005PubMedID: 30074091OAI: oai:DiVA.org:umu-151059DiVA, id: diva2:1245078
Available from: 2018-09-04 Created: 2018-09-04 Last updated: 2018-09-04Bibliographically approved

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Bergström, SvenNormark, Johan

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Public Health, Global Health, Social Medicine and Epidemiology

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