umu.sePublications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Effect and feasibility of non-linear periodized resistance training in people with COPD: study protocol for a randomized controlled trial
Umeå University, Faculty of Medicine, Department of Community Medicine and Rehabilitation.ORCID iD: 0000-0002-3212-4708
Show others and affiliations
2019 (English)In: Trials, ISSN 1745-6215, E-ISSN 1745-6215, Vol. 20, no 1, article id 6Article in journal (Refereed) Published
Abstract [en]

BACKGROUND: In people with chronic obstructive pulmonary disease (COPD), limb-muscle dysfunction is one of the most troublesome systemic manifestations of the disease, which at the functional level is evidenced by reduced strength and endurance of limb muscles. Improving limb-muscle function is an important therapeutic goal of COPD management, for which resistance training is recommended. However, current guidelines for resistance training in COPD mainly focus on improving muscle strength which only reflects one aspect of limb-muscle function and does not address the issue of reduced muscle endurance. The latter is of importance considering that the reduction in limb-muscle endurance often is greater than that of muscle weakness, and also, limb-muscle endurance seems to be closer related to walking capacity as well as arm function than to limb-muscle strength within this group of people. Thus, strategies targeting multiple aspects of the decreased muscle function are warranted to increase the possibility for an optimal effect for the individual patient. Periodized resistance training, which represents a planned variation of resistance training variables (i.e., volume, intensity, frequency, etc.), is one strategy that could be used to target limb-muscle strength as well as limb-muscle endurance within the same exercise regimen.

METHODS: This is an international, multicenter, randomized controlled trial comparing the effect and feasibility of non-linear periodized resistance training to traditional non-periodized resistance training in people with COPD. Primary outcomes are dynamic limb-muscle strength and endurance. Secondary outcomes include static limb-muscle strength and endurance, functional performance, quality of life, dyspnea, intramuscular adaptations as well as the proportion of responders. Feasibility of the training programs will be assessed and compared on attendance rate, duration, satisfaction, drop-outs as well as occurrence and severity of any adverse events.

DISCUSSION: The proposed trial will provide new knowledge to this research area by investigating and comparing the feasibility and effects of non-linear periodized resistance training compared to traditional non-periodized resistance training. If the former strategy produces larger physiological adaptations than non-periodized resistance training, this project may influence the prescription of resistance training in people with COPD.

TRIAL REGISTRATION: ClinicalTrials.gov, ID: NCT03518723 . Registered on 13 April 2018.

Place, publisher, year, edition, pages
BioMed Central, 2019. Vol. 20, no 1, article id 6
Keywords [en]
Functional performance, Limb-muscle endurance, Limb-muscle strength, Pulmonary disease, chronic obstructive
National Category
Physiotherapy
Research subject
physiotherapy
Identifiers
URN: urn:nbn:se:umu:diva-154980DOI: 10.1186/s13063-018-3129-yISI: 000454906600006PubMedID: 30606240OAI: oai:DiVA.org:umu-154980DiVA, id: diva2:1275689
Funder
Swedish Research Council, 2016-01802Swedish Heart Lung Foundation, E 127/16Available from: 2019-01-07 Created: 2019-01-07 Last updated: 2019-01-25Bibliographically approved

Open Access in DiVA

fulltext(1773 kB)76 downloads
File information
File name FULLTEXT01.pdfFile size 1773 kBChecksum SHA-512
3f46d23ab62ecce44306bd7d63c6655e17d897b02930e5d738b4cf0e4cc7b66b33c98bb3a2e70d1f4450a60b86bd8ba4facdf854cf37127ea633599f5f33e932
Type fulltextMimetype application/pdf

Other links

Publisher's full textPubMed

Authority records BETA

Frykholm, ErikStål, PerSandström, ThomasSörlin, AnnNyberg, Andre

Search in DiVA

By author/editor
Frykholm, ErikStål, PerSandström, ThomasSörlin, AnnNyberg, Andre
By organisation
Department of Community Medicine and RehabilitationDepartment of Integrative Medical Biology (IMB)Department of Public Health and Clinical Medicine
In the same journal
Trials
Physiotherapy

Search outside of DiVA

GoogleGoogle Scholar
Total: 76 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

doi
pubmed
urn-nbn

Altmetric score

doi
pubmed
urn-nbn
Total: 193 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf