umu.sePublikationer
Ändra sökning
RefereraExporteraLänk till posten
Permanent länk

Direktlänk
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Annat format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf
Peri-implant crevicular fluid proteome before and after adjunctive enamel matrix derivative treatment of peri-implantitis
Umeå universitet, Medicinska fakulteten, Institutionen för odontologi.ORCID-id: 0000-0002-4430-8125
Umeå universitet, Medicinska fakulteten, Institutionen för odontologi. Department of Periodontology, Public Dental Health County Council of Gävleborg, Gävle County Hospital, Gävle, Sweden; Center for Clinical Research and Development, Uppsala University/Region Gävleborg, Gävle, Sweden.ORCID-id: 0000-0002-5327-8028
Umeå universitet, Medicinska fakulteten, Institutionen för odontologi.ORCID-id: 0000-0002-8244-5200
2019 (Engelska)Ingår i: Journal of Clinical Periodontology, ISSN 0303-6979, E-ISSN 1600-051X, Vol. 46, nr 6, s. 669-677Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

Aim: The aim of this study was to explore which peri‐implant crevicular fluid (PICF) protein pattern is associated with the active peri‐implantitis process.

Materials and methods: Peri‐implant crevicular fluid from 25 peri‐implantitis sites were subjected to proteomic analysis using liquid chromatography–tandem mass spectrometry before and at 3, 6 and 12 months after treatment, to identify associations between PICF protein pattern and implant loss, bleeding on probing, pocket depth and enamel matrix derivative (EMD) treatment.

Results: Clustering of subjects based on their 3–12 months PICF proteomic profiles by principal component analysis defined two major clusters. Cluster 2 differentiated from cluster 3 by 52 proteins (R2 = 90%, Q2 = 80%) and belonging to cluster 2 was associated with implant loss (p = 0.009) and bleeding on probing (p = 0.001). Cluster 3 was associated with implant survival and EMD treatment (p = 0.044).

Conclusion: Here, we demonstrate that a specific PICF proteomic profile associates with active peri‐implantitis process and implant loss.

Ort, förlag, år, upplaga, sidor
John Wiley & Sons, 2019. Vol. 46, nr 6, s. 669-677
Nyckelord [en]
enamel matrix derivative, implant, peri-implantitis, proteome
Nationell ämneskategori
Odontologi
Identifikatorer
URN: urn:nbn:se:umu:diva-159844DOI: 10.1111/jcpe.13108ISI: 000468314400008PubMedID: 30985016OAI: oai:DiVA.org:umu-159844DiVA, id: diva2:1323085
Tillgänglig från: 2019-06-11 Skapad: 2019-06-11 Senast uppdaterad: 2019-06-11Bibliografiskt granskad

Open Access i DiVA

Fulltext saknas i DiVA

Övriga länkar

Förlagets fulltextPubMed

Personposter BETA

Esberg, AndersIsehed, CatrineLundberg, Pernilla

Sök vidare i DiVA

Av författaren/redaktören
Esberg, AndersIsehed, CatrineLundberg, Pernilla
Av organisationen
Institutionen för odontologi
I samma tidskrift
Journal of Clinical Periodontology
Odontologi

Sök vidare utanför DiVA

GoogleGoogle Scholar

doi
pubmed
urn-nbn

Altmetricpoäng

doi
pubmed
urn-nbn
Totalt: 61 träffar
RefereraExporteraLänk till posten
Permanent länk

Direktlänk
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Annat format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf