umu.sePublications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Flick of a switch: regulatory mechanisms allowing Listeria monocytogenes to transition from a saprophyte to a killer
Umeå University, Faculty of Medicine, Molecular Infection Medicine Sweden (MIMS). Umeå University, Faculty of Medicine, Umeå Centre for Microbial Research (UCMR). Umeå University, Faculty of Medicine, Department of Molecular Biology (Faculty of Medicine).
Umeå University, Faculty of Medicine, Molecular Infection Medicine Sweden (MIMS). Umeå University, Faculty of Medicine, Umeå Centre for Microbial Research (UCMR). Umeå University, Faculty of Medicine, Department of Molecular Biology (Faculty of Medicine).
Show others and affiliations
2019 (English)In: Microbiology, ISSN 1350-0872, E-ISSN 1465-2080, Vol. 165, no 8, p. 819-833Article, review/survey (Refereed) Published
Abstract [en]

In contrast to obligate intracellular pathogens that can remain in relatively stable host-associated environments, the soil-living bacterial pathogen Listeria monocytogenes has to sense and respond to physical and chemical cues in a variety of quite different niches. In particular, the bacterium has to survive the dramatic transition from its saprophytic existence to life within the host where nutritional stress, increased temperature, acidity, osmotic stress and the host defences present a new and challenging landscape. This review focuses on the sB and PrfA regulatory systems used by L. monocytogenes to sense the changing environment and implement survival mechanisms that help to overcome the disparate conditions within the host, but also to switch from a harmless saprophyte to an impressively effective pathogen.

Place, publisher, year, edition, pages
MICROBIOLOGY SOC , 2019. Vol. 165, no 8, p. 819-833
Keywords [en]
Listeria monocytogenes, sigma B, PrfA, virulence, light-sensing
National Category
Microbiology
Identifiers
URN: urn:nbn:se:umu:diva-162311DOI: 10.1099/mic.0.000808ISI: 000478025200002PubMedID: 31107205OAI: oai:DiVA.org:umu-162311DiVA, id: diva2:1343275
Available from: 2019-08-16 Created: 2019-08-16 Last updated: 2019-09-03Bibliographically approved

Open Access in DiVA

No full text in DiVA

Other links

Publisher's full textPubMed

Authority records BETA

Tiensuu, Teresade Oliveira, Ana HenriquesJohansson, Jörgen

Search in DiVA

By author/editor
Tiensuu, TeresaGuerreiro, Duarte N.de Oliveira, Ana HenriquesO'Byrne, ConorJohansson, Jörgen
By organisation
Molecular Infection Medicine Sweden (MIMS)Umeå Centre for Microbial Research (UCMR)Department of Molecular Biology (Faculty of Medicine)
In the same journal
Microbiology
Microbiology

Search outside of DiVA

GoogleGoogle Scholar

doi
pubmed
urn-nbn

Altmetric score

doi
pubmed
urn-nbn
Total: 48 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf