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Aerobic capacity in rheumatoid arthritis: aspects of associations with cardiovascular risk factors and disease activity
Umeå University, Faculty of Medicine, Department of Public Health and Clinical Medicine, Rheumatology.
2018 (English)Licentiate thesis, comprehensive summary (Other academic)
Place, publisher, year, edition, pages
Umeå: Umeå University , 2018. , p. 56
National Category
Rheumatology and Autoimmunity
Identifiers
URN: urn:nbn:se:umu:diva-164592ISBN: 9789178550050 (print)OAI: oai:DiVA.org:umu-164592DiVA, id: diva2:1365338
Available from: 2019-10-24 Created: 2019-10-24 Last updated: 2019-10-24Bibliographically approved
List of papers
1. Aerobic capacity is associated with cardiovascular risk factors and disease activity in early rheumatoid arthritis: a cross sectional study
Open this publication in new window or tab >>Aerobic capacity is associated with cardiovascular risk factors and disease activity in early rheumatoid arthritis: a cross sectional study
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2018 (English)In: Article in journal (Other academic) Submitted
Keywords
rheumatoid arthritis, aerobic capacity, subclinical atherosclerosis, body composition, cardiovascular disease risk
National Category
Rheumatology and Autoimmunity
Identifiers
urn:nbn:se:umu:diva-164590 (URN)
Available from: 2019-10-24 Created: 2019-10-24 Last updated: 2019-10-24
2. Benefits of spinning exercise on cardiovascular risk factors in rheumatoid arthritis: a pilot study
Open this publication in new window or tab >>Benefits of spinning exercise on cardiovascular risk factors in rheumatoid arthritis: a pilot study
2014 (English)In: Cardiopulmonary Physical Therapy Journal, ISSN 1541-7891, Vol. 25, no 3, p. 68-74Article in journal (Refereed) Published
Abstract [en]

Purpose: Rheumatoid arthritis (RA) is associated with an increased risk of cardiovascular disease (CVD). Exercise is known to reduce this risk in the general population but the cardiovascular effects in patients with RA need further study. The purpose of this pilot study was to examine the effects of spinning exercise on the traditional risk factors for CVD, aerobic capacity and inflammation in patients with RA.

Methods: Thirteen subjects (12 females, 1 male; median age 57 years) attended intensive spinning sessions lasting 45 minutes, 3 times per week for 10 weeks. Measurements at baseline and at 10 and 25 weeks were aerobic capacity, pulse wave analysis with aortic and peripheral blood pressure (BP), disease activity (CRP, ESR, tender and swollen joints and global health assessment), blood lipid levels, body mass index (BMI), functional ability, and subjective diary notes. Friedman's test and the paired Wilcoxon rank sum test were used to measure changes over time. Correlation analyses were made by the Spearman rank correlation method.

Results: There were significant improvements over time in aerobic capacity, systolic BP, BMI and tender joint count (p<0.05). After 10 weeks the subjects showed significant improvements in terms of aerobic capacity (+7 ml O2/kg x min; p<0.05), systolic BP (-10.8 mm Hg; p<0.01) and tender joint count (p<0.05). After 25 weeks there was still a significant improvement in systolic BP (p<0.05) compared to baseline.

Conclusions: Intensive spinning exercise for 10 weeks induced a clinically relevant improvement in aerobic capacity and BP. No detrimental effect on disease activity was recorded.

Place, publisher, year, edition, pages
Wolters Kluwer, 2014
Keywords
aerobic capacity, exercise, blood pressure
National Category
Rheumatology and Autoimmunity
Identifiers
urn:nbn:se:umu:diva-120817 (URN)
Available from: 2016-05-23 Created: 2016-05-23 Last updated: 2019-10-24Bibliographically approved

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Ångström, Lars

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