umu.sePublications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Virulence and Pathogenicity Properties of Aggregatibacter actinomycetemcomitans
Division of Oral Diseases, Department of Dental Medicine, Karolinska Institutet, S-141 04 Huddinge, Sweden.
Department of Biochemistry, University of Turku, FI-20014 Turku, Finland.
Division of Oral Diseases, Department of Dental Medicine, Karolinska Institutet, S-141 04 Huddinge, Sweden.
Umeå University, Faculty of Medicine, Department of Odontology. (Aa-gruppen)
Show others and affiliations
2019 (English)In: Pathogens, ISSN 2076-0817, Vol. 8, no 4, article id E222Article in journal (Refereed) Published
Abstract [en]

Aggregatibacter actinomycetemcomitans is a periodontal pathogen colonizing the oral cavity of a large proportion of the human population. It is equipped with several potent virulence factors that can cause cell death and induce or evade inflammation. Because of the large genetic diversity within the species, both harmless and highly virulent genotypes of the bacterium have emerged. The oral condition and age, as well as the geographic origin of the individual, influence the risk to be colonized by a virulent genotype of the bacterium. In the present review, the virulence and pathogenicity properties of A. actinomycetemcomitans will be addressed.

Place, publisher, year, edition, pages
Basel: MDPI, 2019. Vol. 8, no 4, article id E222
Keywords [en]
Aggregatibacter actinomycetemcomitans, biofilm, cytokine binding factors, cytolethal distending toxin, horizontal gene transfer, leukotoxin, lipopolysaccharides, outer membrane vesicles, proteomic
National Category
Medical Biotechnology (with a focus on Cell Biology (including Stem Cell Biology), Molecular Biology, Microbiology, Biochemistry or Biopharmacy)
Identifiers
URN: urn:nbn:se:umu:diva-165083DOI: 10.3390/pathogens8040222PubMedID: 31698835OAI: oai:DiVA.org:umu-165083DiVA, id: diva2:1368981
Funder
Swedish Research Council, 2017-01198Västerbotten County Council, 7003193Available from: 2019-11-09 Created: 2019-11-09 Last updated: 2019-11-19Bibliographically approved

Open Access in DiVA

fulltext(1049 kB)0 downloads
File information
File name FULLTEXT01.pdfFile size 1049 kBChecksum SHA-512
2cc46b8a23becfe04e4aad133a3548698e6467000beead1b00fbf120fbd499ae446557e38ce130dc27792835d111325506144e37188116c81caf509a5e72c5d0
Type fulltextMimetype application/pdf

Other links

Publisher's full textPubMed

Authority records BETA

Lindholm, MarkOscarsson, JanJohansson, Anders

Search in DiVA

By author/editor
Lindholm, MarkOscarsson, JanJohansson, Anders
By organisation
Department of Odontology
Medical Biotechnology (with a focus on Cell Biology (including Stem Cell Biology), Molecular Biology, Microbiology, Biochemistry or Biopharmacy)

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

doi
pubmed
urn-nbn

Altmetric score

doi
pubmed
urn-nbn
Total: 11 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf