umu.sePublications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
The effect of botulinum toxin injections on bruxism: A systematic review
Umeå University, Faculty of Medicine, Department of Odontology.ORCID iD: 0000-0001-5992-8135
2019 (English)In: Journal of Oral Rehabilitation, ISSN 0305-182X, E-ISSN 1365-2842Article in journal (Refereed) Epub ahead of print
Abstract [en]

Botulinum neurotoxins are produced by the gram-positive anaerobic bacteria Clostridium botulinum, of which several different serotypes have been identified 1,2 . Botulinum neurotoxin type A (BTA) is clinically used the most due to the longer duration of its effect 3,4 and is the focus of this article. One of the first to investigate BTA was Brooks, as he in 1953, showed that when injecting BTA in muscle tissue it inhibited the release of Acetylcholine (ACh) at the neuromuscular junction and rendered motor nerve filaments unexcitable 3 . It has since been shown that BTA inhibits synaptosomal nerve-associated protein 25 (SNAP-25), a protein involved in the release of ACh filled vesicles into the synaptic cleft through the assembly of the soluble N-ethylmaleimide-sensitive fusion protein attachment protein receptors (SNARE) complex, which is necessary for docking and fusing neurotransmitter vesicles with neuronal membranes.

Place, publisher, year, edition, pages
2019.
Keywords [en]
Bite Force, Botulinum Toxins, Bruxism, Electromyography, Review, Tooth Wear
National Category
Dentistry
Research subject
Odontology
Identifiers
URN: urn:nbn:se:umu:diva-165601DOI: 10.1111/joor.12914PubMedID: 31769044OAI: oai:DiVA.org:umu-165601DiVA, id: diva2:1373716
Available from: 2019-11-27 Created: 2019-11-27 Last updated: 2019-11-28

Open Access in DiVA

No full text in DiVA

Other links

Publisher's full textPubMed

Authority records BETA

Pettersson, Mattias

Search in DiVA

By author/editor
Ågren, MartinSahin, ChristoferPettersson, Mattias
By organisation
Department of Odontology
In the same journal
Journal of Oral Rehabilitation
Dentistry

Search outside of DiVA

GoogleGoogle Scholar

doi
pubmed
urn-nbn

Altmetric score

doi
pubmed
urn-nbn
Total: 13 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf