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Consumption of nuts and seeds and pancreatic ductal adenocarcinoma risk in the European Prospective Investigation into Cancer and Nutrition
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2020 (English)In: International Journal of Cancer, ISSN 0020-7136, E-ISSN 1097-0215, Vol. 146, no 1, p. 76-84Article in journal (Refereed) Published
Abstract [en]

Four epidemiologic studies have assessed the association between nut intake and pancreatic cancer risk with contradictory results. The present study aims to investigate the relation between nut intake (including seeds) and pancreatic ductal adenocarcinoma (PDAC) risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Cox proportional hazards models were used to estimate hazards ratio (HR) and 95% confidence intervals (95% CI) for nut intake and PDAC risk. Information on intake of nuts was obtained from the EPIC country-specific dietary questionnaires. After a mean follow-up of 14 years, 476,160 participants were eligible for the present study and included 1,283 PDAC cases. No association was observed between consumption of nuts and PDAC risk (highest intake vs nonconsumers: HR, 0.89; 95% CI, 0.72-1.10; p-trend = 0.70). Furthermore, no evidence for effect-measure modification was observed when different subgroups were analyzed. Overall, in EPIC, the highest intake of nuts was not statistically significantly associated with PDAC risk.

Place, publisher, year, edition, pages
Wiley-Blackwell, 2020. Vol. 146, no 1, p. 76-84
Keywords [en]
pancreatic cancer, nuts, seeds, diet, intake, EPIC, prospective cohort study
National Category
Cancer and Oncology Nutrition and Dietetics
Identifiers
URN: urn:nbn:se:umu:diva-165785DOI: 10.1002/ijc.32415ISI: 000495546500011PubMedID: 31107546OAI: oai:DiVA.org:umu-165785DiVA, id: diva2:1374892
Funder
Swedish Cancer SocietyRegion SkåneVästerbotten County CouncilAvailable from: 2019-12-03 Created: 2019-12-03 Last updated: 2019-12-03Bibliographically approved

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Sund, Malin

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Boutron-Ruault, Marie-ChristineOvervad, KimSciannameo, VeronicaSund, Malin
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Citation style
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