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Activities of daily living in Parkinson's disease: Time/gender perspective
Umeå universitet, Medicinska fakulteten, Institutionen för samhällsmedicin och rehabilitering.ORCID-id: 0000-0002-8417-1768
Department of Neurology, University Medical Centre Ljubljana, Ljubljana, Slovenia; Faculty of Computer Sciences and Informatics, University of Ljubljana, Ljubljana, Slovenia; Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.ORCID-id: 0000-0003-1832-3441
Umeå universitet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.ORCID-id: 0000-0002-2348-1164
Umeå universitet, Medicinska fakulteten, Institutionen för farmakologi och klinisk neurovetenskap.
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2019 (Engelska)Ingår i: Acta Neurologica Scandinavica, ISSN 0001-6314, E-ISSN 1600-0404Artikel i tidskrift (Refereegranskat) Epub ahead of print
Abstract [en]

Objective: The objectives of this study were to explore the changes in the activities of daily living (ADL) in persons with Parkinson's disease (pwPD) over time and to investigate possible differences in ADL performance between men and women with PD.

Materials & Methods: One hundred twenty‐nine persons (76 men) with a clinically established PD self‐assessed their ADL performance from the time of diagnosis up to 8 years follow‐up using the ADL taxonomy. Other demographic and clinical data (motor state, cognition, depression) were also collected and subjected to further analysis.

Results: Nine of 12 domains in the ADL taxonomy showed a change over time (Eating and Drinking [P = .009], Mobility [P < .001], Toilet activities [P = .031], Dressing [P < .001], Personal hygiene [P < .001], Communication [P < .001], Cooking [P = .001], Shopping [P < .001] and Cleaning [P < .001]). In addition to time, two domains, (Shopping [P = .007] and Cleaning [P = .027]) also showed an effect of gender with worse scores in women. The nine ADL domains showing effect of time, showed temporary improvement at 12 months follow‐up, most probably due to dopaminergic medication. All nine domains deteriorated at later follow‐up.

Conclusions: As expected, there was deterioration in self‐assessed performance in the majority od ADL domains over time. Women assessed their ADLs worse in two domains (Shopping and Cleaning) probably reflecting a general gender‐related activity pattern rather than being a PD‐specific finding.

Ort, förlag, år, upplaga, sidor
2019.
Nyckelord [en]
activities of daily living, gender differences, longitudinal study, Parkinson's disease
Nationell ämneskategori
Neurologi
Identifikatorer
URN: urn:nbn:se:umu:diva-166577DOI: 10.1111/ane.13189ISI: 000497350700001PubMedID: 31693751OAI: oai:DiVA.org:umu-166577DiVA, id: diva2:1380634
Tillgänglig från: 2019-12-19 Skapad: 2019-12-19 Senast uppdaterad: 2019-12-19

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Sperens, MariaGeorgiev, DejanDomellöf, Magdalena E.Forsgren, LarsHamberg, KatarinaHariz, Gun-Marie

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Sperens, MariaGeorgiev, DejanDomellöf, Magdalena E.Forsgren, LarsHamberg, KatarinaHariz, Gun-Marie
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Institutionen för samhällsmedicin och rehabiliteringInstitutionen för psykologiInstitutionen för farmakologi och klinisk neurovetenskapAllmänmedicin
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