umu.sePublications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
A Method for Identification of Mechanical Response of Motor Units in Skeletal Muscle Voluntary Contractions using Ultrafast Ultrasound Imaging: Simulations and Experimental Tests
Umeå University, Faculty of Medicine, Department of Radiation Sciences.ORCID iD: 0000-0003-4328-5467
Department of Clinical Neurophysiology, Department of Neurosciences, University Hospital, Uppsala University, Sweden.
Umeå University, Faculty of Medicine, Department of Radiation Sciences.ORCID iD: 0000-0002-3423-2083
Umeå University, Faculty of Science and Technology, Department of Mathematics and Mathematical Statistics. (Mathematical Statistics)ORCID iD: 0000-0001-5673-620x
Show others and affiliations
2020 (English)In: IEEE Access, E-ISSN 2169-3536, Vol. 8, p. 50299-50311Article in journal (Refereed) Published
Abstract [en]

The central nervous system coordinates movement through forces generated by motor units (MUs) in skeletal muscles. To analyze MUs function is essential in sports, rehabilitation medicine applications, and neuromuscular diagnostics. The MUs and their function are studied using electromyography. Typically, these methods study only a small muscle volume (1 mm3) or only a superficial (< 1 cm) volume of the muscle. Here we introduce a method to identify so-called mechanical units, i.e., the mechanical response of electrically active MUs, in the whole muscle (4x4 cm, cross-sectional) under voluntary contractions by ultrafast ultrasound imaging and spatiotemporal decomposition. We evaluate the performance of the method by simulation of active MUs' mechanical response under weak contractions. We further test the experimental feasibility on eight healthy subjects. We show the existence of mechanical units that contribute to the tissue dynamics in the biceps brachii at low force levels and that these units are similar to MUs described by electromyography with respect to the number of units, territory sizes, and firing rates. This study introduces a new potential neuromuscular functional imaging method, which could be used to study a variety of questions on muscle physiology that previously were difficult or not possible to address.

Place, publisher, year, edition, pages
IEEE, 2020. Vol. 8, p. 50299-50311
Keywords [en]
Biomedical engineering, Blind source separation, Physiology, Ultrasonic imaging
National Category
Medical Image Processing Physiology Probability Theory and Statistics
Identifiers
URN: urn:nbn:se:umu:diva-168944DOI: 10.1109/ACCESS.2020.2980053ISI: 000524898700010OAI: oai:DiVA.org:umu-168944DiVA, id: diva2:1414593
Funder
Swedish Research Council, 2015-04461The Kempe Foundations, JCK-1115Available from: 2020-03-13 Created: 2020-03-13 Last updated: 2020-04-24Bibliographically approved

Open Access in DiVA

fulltext(3608 kB)31 downloads
File information
File name FULLTEXT02.pdfFile size 3608 kBChecksum SHA-512
43516d89979ae162b3695196522a98fbc0cfed0be1bc4453016d2a7012571b9fa52b557227ebe501671c0ea6f7b9e9f4ad49babf1675043a5098691f47bcce81
Type fulltextMimetype application/pdf

Other links

Publisher's full text

Authority records BETA

Rohlén, RobinStoverud, Karen-HeleneYu, JunGrönlund, Christer

Search in DiVA

By author/editor
Rohlén, RobinStoverud, Karen-HeleneYu, JunGrönlund, Christer
By organisation
Department of Radiation SciencesDepartment of Mathematics and Mathematical Statistics
In the same journal
IEEE Access
Medical Image ProcessingPhysiologyProbability Theory and Statistics

Search outside of DiVA

GoogleGoogle Scholar
Total: 39 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

doi
urn-nbn

Altmetric score

doi
urn-nbn
Total: 167 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf