Investigation of Amine-Buffered Amide Reagents for Coulometric Karl Fischer Titration
2009 (English)In: Talanta: The International Journal of Pure and Applied Analytical Chemistry, ISSN 0039-9140, Vol. 78, no 4-5, 1452-1457 p.Article in journal (Refereed) Published
Formamide (FA), N-methylformamide (NMF), and dimethylformamide (DMF),were evaluated as solvents for coulometric Karl Fischer (KF) reagents in combination with several amine bases. Except for the effect of the iodine species (iodine or triiodide), the pH of the reagent and the position of the sulfur dioxide/ hydrogen sulfite equilibrium were found to be the main factors explaining the large difference in the observed reaction rates betweenwater and the KF reagent in these solvents. Acid–base titrations showed that hydrogen sulfite is the main sulfur reactant in these media. The results will be of great importance in finding suitable combinations of base and solvent with respect to stoichiometry, side reactions caused by active carbonyl compounds, and reagent stability.
Place, publisher, year, edition, pages
2009. Vol. 78, no 4-5, 1452-1457 p.
non-alcoholic KF reagent, water determination, amide, amine
IdentifiersURN: urn:nbn:se:umu:diva-3628DOI: 10.1016/j.talanta.2009.02.047OAI: oai:DiVA.org:umu-3628DiVA: diva2:142418