Playing soccer increases serum concentrations of the biochemical markers of brain damage S-100B and neuron-specific enolase in elite players: a pilot study
2004 (English)In: Brain Injury, ISSN 0269-9052, E-ISSN 1362-301x, Vol. 18, no 9, 899-909 p.Article in journal (Refereed) Published
Primary objective : To analyse serum concentrations of two biochemical markers of brain tissue damage, S-100B and NSE (neurone-specific enolase), in male soccer players in connection to the game. Methods : Blood samples were taken in players before and after a competitive game and the numbers of headers and of trauma events during soccer play were assessed. Results : Both S-100B and NSE were significantly raised in serum samples obtained after the game in comparison with the pre-game values (S-100B: 0.118 ± 0.040 µg L -1 vs 0.066 ± 0.025 µg L -1 , p < 0.001; NSE: 10.29 ± 2.16 µg L -1 vs 8.57 ± 2.31 µg L -1 , p < 0.001). Only changes in S-100B concentrations (post-game minus pre-game values) were statistically significantly correlated to the number of headers ( r = 0.428, p = 0.02) and to the number of other trauma events ( r = 0.453, p = 0.02). Conclusion : Playing competitive elite soccer was found to cause increase in serum concentrations of S-100B and NSE. Increases in S-100B were significantly correlated to the number of headers, and heading may accordingly have contributed to these increases.
Place, publisher, year, edition, pages
Taylor & Francis Ltd , 2004. Vol. 18, no 9, 899-909 p.
Adult, Biological Markers/blood, Brain Concussion/blood, Craniocerebral Trauma/blood/etiology, Fatigue/etiology, Humans, Male, Nerve Growth Factors, Phosphopyruvate Hydratase/*blood, Pilot Projects, S100 Proteins/*blood, Sleep Disorders/etiology, Soccer/injuries
IdentifiersURN: urn:nbn:se:umu:diva-3930DOI: 10.1080/02699050410001671865PubMedID: 15223742OAI: oai:DiVA.org:umu-3930DiVA: diva2:142842