Change search
ReferencesLink to record
Permanent link

Direct link
The association of bacterial adhesion with dental caries.
Umeå University, Faculty of Medicine, Odontology, Cariology.
Umeå University, Faculty of Medicine, Odontology, Cariology.
Show others and affiliations
2001 (English)In: Journal of Dental Research, Vol. 80, no 11, 2005-10 p.Article in journal (Refereed) Published
Abstract [en]

Saliva adhesion of bacteria is a key event in oral biofilm formation. Here, we used partial least-squares (PLS) analysis to correlate adhesion of cariogenic (Streptococcus mutans Ingbritt) and commensal (Actinomyces naeslundii LY7) model bacteria, and their agglutinin and acidic proline-rich protein ligands, respectively, with high and low caries experiences in 38 children reflecting today's skewed caries distribution. Adhesion of S. mutans was among the factors correlating strongest with high caries experience when PLS modeled together with traditional factors (e.g., sugar intake, lactobacilli counts). Saliva phenotypes with high agglutinin levels and Db-s (an acidic PRP variant) coincided with both high caries experience and S. mutans adhesion. A. naeslundii adhesion correlated with low caries experience. Non-Db phenotypes (i.e., acidic PRP-1 and PRP-2 variants) coincided with both low caries experience and S. mutans, but high A. naeslundii, adhesion. Thus, bacterial adhesion may modulate susceptibility and resistance to dental caries.

Place, publisher, year, edition, pages
2001. Vol. 80, no 11, 2005-10 p.
URN: urn:nbn:se:umu:diva-6150PubMedID: 11759011OAI: diva2:145818
Available from: 2008-02-12 Created: 2008-02-12 Last updated: 2009-07-31Bibliographically approved

Open Access in DiVA

No full text


Search in DiVA

By author/editor
Nordlund, ÅkeJohansson, IngegerdStrömberg, Nicklas
By organisation

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 54 hits
ReferencesLink to record
Permanent link

Direct link