umu.sePublications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Myocardial systolic function increases during positive pressure lung inflation.
Umeå University, Faculty of Medicine, Department of Surgical and Perioperative Sciences, Anaesthesiology.
Umeå University, Faculty of Medicine, Department of Surgical and Perioperative Sciences, Anaesthesiology.ORCID iD: 0000-0002-5325-2688
Umeå University, Faculty of Medicine, Department of Surgical and Perioperative Sciences, Anaesthesiology.
Umeå University, Faculty of Medicine, Department of Surgical and Perioperative Sciences, Anaesthesiology.
2005 (English)In: Anesthesia and Analgesia, ISSN 0003-2999, Vol. 101, no 5, 1269-74 p.Article in journal (Refereed) Published
Abstract [en]

Lung inflation with positive airway pressure may have rapid and dynamic effects on myocardial contractile function. We designed this study to assess the magnitude and time to onset of myocardial function changes during the initiation of single positive pressure lung inflation at clinically relevant inflation pressures. In 8 anesthetized 40-kg pigs, left ventricular pressures and volumes were measured directly (conductance volumetry). A 15 cm H2O airway pressure plateau with lung inflation (PPLI-15) was performed, and 2 single beats from that sequence, one from resting apnea at zero airway pressure and the second from the point when the lungs were first maximally inflated, were selected for analysis. Systolic function variables for zero airway pressure and PPLI-15 were analyzed. Systolic elastance, derived from bilinear time-varying elastance curves, increased approximately 15% during PPLI-15 from zero airway pressure. This agreed with other systolic function variables that identified an increase in left ventricular contractile function for the lung inflation beat. Serial measurements of myocardial function should be conducted with constant airway pressure and lung inflation conditions.

Place, publisher, year, edition, pages
2005. Vol. 101, no 5, 1269-74 p.
Keyword [en]
Animals, Lung/physiopathology, Positive-Pressure Respiration, Swine, Systole, Ventricular Function; Left
Identifiers
URN: urn:nbn:se:umu:diva-6810PubMedID: 16243979OAI: oai:DiVA.org:umu-6810DiVA: diva2:146480
Available from: 2007-12-18 Created: 2007-12-18 Last updated: 2015-09-15Bibliographically approved

Open Access in DiVA

fulltext(99 kB)240 downloads
File information
File name FULLTEXT01.pdfFile size 99 kBChecksum SHA-512
d68e3e91867d0abb286297055b8208861a421acf72aeac25ad75621c0cfbd58480b65dd7a9f6d3b69764aaa9db5cc30f03a57e74db0aecaf69af90ccc27724e4
Type fulltextMimetype application/pdf

Other links

PubMedhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Retrieve&list_uids=16243979&dopt=Citation

Search in DiVA

By author/editor
Haney, Michael FJohansson, GöranHäggmark, Sören
By organisation
Anaesthesiology

Search outside of DiVA

GoogleGoogle Scholar
Total: 240 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

pubmed
urn-nbn

Altmetric score

pubmed
urn-nbn
Total: 73 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf