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11beta-HSD1 inhibition improves triglyceridemia through reduced liver VLDL secretion and partitions lipids toward oxidative tissues.
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2007 (English)In: Am J Physiol Endocrinol Metab, ISSN 0193-1849, Vol. 293, no 4, E1045-52 p.Article in journal (Refereed) Published
Place, publisher, year, edition, pages
2007. Vol. 293, no 4, E1045-52 p.
Keyword [en]
11-beta-Hydroxysteroid Dehydrogenase Type 1/*antagonists & inhibitors, Adipose Tissue; Brown/drug effects/metabolism, Animals, Enzyme Inhibitors/pharmacology, Heart/drug effects, Hypertriglyceridemia/blood/*metabolism, Lipid Metabolism/*drug effects, Lipoproteins; VLDL/*drug effects/*secretion, Liver/*drug effects/metabolism, Male, Muscle; Skeletal/drug effects/metabolism, Myocardium/metabolism, Oxidation-Reduction/drug effects, Rats, Rats; Sprague-Dawley, Triazoles/*pharmacology, Triglycerides/*secretion
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URN: urn:nbn:se:umu:diva-6835PubMedID: 17666487OAI: oai:DiVA.org:umu-6835DiVA: diva2:146505
Available from: 2008-01-11 Created: 2008-01-11 Last updated: 2011-01-11Bibliographically approved

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