Evaluation of the structure/cross-reactivity relationship of polycyclic aromatic compounds using an enzyme-linked immunosorbent assay kit
2003 (English)In: Analytica Chimica Acta, ISSN 0003-2670, E-ISSN 1873-4324, Vol. 487, no 1, 43-50 p.Article in journal (Refereed) Published
A commercially available enzyme-linked immunosorbent assay (ELISA) kit, the PAH soil test, was evaluated with regard to cross-reactivity. Phenanthrene in methanol was used as reference substance. Anthracene, naphthalene and fluorene were chosen as representatives of the 16 US-EPA priority-pollutant polycyclic aromatic hydrocarbons (PAHs). In addition, a number of polycyclic aromatic compounds (PACs), including methyl-, phenyl-, and carbonyl-PAHs, as well as NSO-heterocyclic PACs, found at former industrial sites, were chosen for elucidation of structure/cross-reactivity relationships. The study emphasizes the importance of a priori knowledge of sample composition for accurate interpretation of test results.
Place, publisher, year, edition, pages
Elsevier, 2003. Vol. 487, no 1, 43-50 p.
Cross-reactivity, PAH, Immunoassay, ELISA, SARs
IdentifiersURN: urn:nbn:se:umu:diva-9232DOI: 10.1016/S0003-2670(03)00466-5OAI: oai:DiVA.org:umu-9232DiVA: diva2:148903
Papers Resulting from the Fifth Workshop on Biosensors and Biological Techniques in Environmental Analysis2008-03-122008-03-122013-11-11Bibliographically approved