umu.sePublications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Corrosion of dental nickel-aluminum bronze with a minor gold content-mechanism and biological impact.
Umeå University, Faculty of Medicine, Odontology.
Umeå University, Faculty of Science and Technology, Chemistry.
2009 (English)In: Journal of Biomedical Materials Research Part B: Applied Biomaterials, ISSN 1552-4981, Vol. 88B, no 2, 465-73 p.Article in journal (Refereed) Published
Abstract [en]

Objectives: To study corrosion and to evaluate biological effects in vitro of corrosion products of a copper-aluminum-nickel alloy with 2% gold. Methods: The alloy NPGTM+2 with the nominal composition Cu:77.3; Al:7.8; Ni:4.3; Fe:3.0; Zn:2.7; Au:2.0; and Mn:1.7 was characterized. Static immersion in acidic saline, pH 2.2-2.4, was used to determine release of metallic elements in a milieu simulating the condition of plaque build-up in interproximal areas of the tooth. Corrosion and surface reactions in saline and artificial saliva were studied by electrochemical techniques including registration of open-circuit-potentials, polarization curves and impedance spectra. Extracts were made in cell culture media and acidic saline and used for MTT test for cytotoxicity and HET-CAM method for irritation. Results: The mean amount of elements released in the acidic saline were in g cm-2 : Cu:632; Al:210; Ni:144; Fe:122; Zn:48; Mn:52. No protective film was formed on the surface of the alloy, as extensive corrosion was observed in both saline and artificial saliva. The corrosion rate was higher in saline than in artificial saliva. Acidic extracts of the alloy diluted up to 64 times reduced cell viability with 80% or more. The extract induced coagulation of the blood vessels of the CAM and was rated as moderate irritant solution. Significance: The nickel-aluminum bronze showed high corrosion rate caused by an inability to create a protective surface layer. High levels of toxic elements were found after static immersion testing, and the corrosion products had a distinct adverse effect on the biological activity.

Place, publisher, year, edition, pages
2009. Vol. 88B, no 2, 465-73 p.
Keyword [en]
alloy, copper, aluminum, gold, corrosion, cell culture, cytotoxicity, HET-CAM, irritant, biocompatibility
Identifiers
URN: urn:nbn:se:umu:diva-10117DOI: doi:10.1002/jbm.b.31143PubMedID: 18546197OAI: oai:DiVA.org:umu-10117DiVA: diva2:149788
Available from: 2009-01-09 Created: 2009-01-09 Last updated: 2009-09-30Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full textPubMed

Authority records BETA

Ardlin, Berit ILindholm-Sethson, Britta

Search in DiVA

By author/editor
Ardlin, Berit ILindholm-Sethson, Britta
By organisation
OdontologyChemistry

Search outside of DiVA

GoogleGoogle Scholar

doi
pubmed
urn-nbn

Altmetric score

doi
pubmed
urn-nbn
Total: 207 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf