Thalamic deep brain stimulation in the treatment of essential tremor: a long-term follow-up
2007 (English)In: British Journal of Neurosurgery, ISSN 0268-8697, E-ISSN 1360-046X, Vol. 21, no 5, 504-509 p.Article in journal (Refereed) Published
Deep brain stimulation (DBS) of the nucleus ventralis intermedius thalami (Vim) in the treatment of essential tremor (ET) is well documented concerning the acute effects. Reports of the long-term effects are, however, few and the aim of the present study was to analyse the long-term efficacy of this treatment. Nineteen patients operated with unilateral Vim-DBS were evaluated with the Essential Tremor Rating Scale (ETRS) before surgery, and after a mean time of 1 and 7 years after surgery. The ETRS score for tremor of the contralateral hand was reduced from 6.8 at baseline to 1.2 and 2.7, respectively, on stimulation at follow-up. For hand function (item 11 – 14) the score was reduced from 12.7 to 4.1 and 8.2, respectively. Vim-DBS is an efficient treatment for ET, also after many years of treatment. There is, however, a decreasing effect over time, most noticeable concerning tremor of action.
Read More: http://informahealthcare.com/doi/abs/10.1080/02688690701552278
Place, publisher, year, edition, pages
2007. Vol. 21, no 5, 504-509 p.
Activities of Daily Living, Adolescent, Adult, Aged, Aged; 80 and over, Deep Brain Stimulation/*methods, Essential Tremor/diagnosis/surgery/*therapy, Female, Follow-Up Studies, Humans, Male, Middle Aged, Prospective Studies, Thalamus, Treatment Outcome
IdentifiersURN: urn:nbn:se:umu:diva-10668DOI: 10.1080/02688690701552278PubMedID: 17922323OAI: oai:DiVA.org:umu-10668DiVA: diva2:150339