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European surveillance study on antimicrobial susceptibility of Gram-positive anaerobic cocci
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2008 (English)In: International Journal of Antimicrobial Agents, ISSN 0924-8579, E-ISSN 1872-7913, Vol. 31, no 4, p. 316-320Article in journal (Refereed) Published
Abstract [en]

Gram-positive anaerobic cocci (GPAC) are a heterogeneous group of microorganisms frequently isolated from local and systemic infections. In this study, the antimicrobial susceptibilities of clinical strains isolated in 10 European countries were investigated. After identification of 299 GPAC to species level, the minimum inhibitory concentrations of penicillin, imipenem, clindamycin, metronidazole, vancomycin and linezolid were determined by the agar dilution method according to the Clinical and Laboratory Standards Institute. The majority of isolates were identified as Finegoldia magna and Parvimonas micra (formerly Peptostreptococcus micros), isolated from skin and soft tissue infections. All isolates were susceptible to imipenem, metronidazole, vancomycin and linezolid. Twenty-one isolates (7%) were resistant to penicillin (n=13) and/or to clindamycin (n=12). Four isolates were resistant to both agents. The majority of resistant isolates were identified as F. magna and originated from blood, abscesses and soft tissue infections.

Place, publisher, year, edition, pages
Amsterdam: Elsevier , 2008. Vol. 31, no 4, p. 316-320
Keyword [en]
Antibiotikaresistens, kliniska isolat, anaeroba kocker
National Category
Microbiology in the medical area
Identifiers
URN: urn:nbn:se:umu:diva-11224DOI: 10.1016/j.ijantimicag.2007.11.006PubMedID: 18180149OAI: oai:DiVA.org:umu-11224DiVA, id: diva2:150895
Available from: 2008-12-01 Created: 2008-12-01 Last updated: 2018-03-15Bibliographically approved

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