Change search
ReferencesLink to record
Permanent link

Direct link
Hand muscle pathology after long-term vibration exposure.
Umeå University, Faculty of Medicine, Public Health and Clinical Medicine, Occupational and Enviromental Medicine.
Umeå University, Faculty of Medicine, Integrative Medical Biology, Anatomy.
Show others and affiliations
2004 (English)In: Journal of Hand Surgery-British and European volume, ISSN 0266-7681, Vol. 29, no 5, 431-7 p.Article in journal (Refereed) Published
Abstract [en]

The morphology of the abductor pollicis brevis muscle was studied in 20 patients suffering from hand-arm vibration syndrome. The main morphological changes observed were centrally located myonuclei and fibre type grouping (found in all 20 muscle biopsies), angulated muscle fibres (found in 19 biopsies), ring fibres and regenerating fibres (found in 18 biopsies) and fibrosis (found in 17 biopsies). The observed abnormalities are believed to reflect damage to both the muscle fibres and the motor nerve. The changes were related to different vibration exposure parameters. The number of fibres demonstrating centrally located nuclei correlated significantly with the cumulative vibration exposure, while the number of angulated fibres correlated significantly with the total vibration exposure time. This indicates that the vibrating tools may cause direct damage to muscle fibres as well as nerves.

Place, publisher, year, edition, pages
2004. Vol. 29, no 5, 431-7 p.
Keyword [en]
Adult, Aged, Biopsy, Cell Nucleus/pathology, Fibrosis, Hand/*pathology, Humans, Male, Middle Aged, Muscle Fibers/*pathology/physiology, Muscle; Skeletal/*pathology, Necrosis, Occupational Diseases/*complications, Regeneration/physiology, Sensation Disorders/etiology, Staining and Labeling, Sweden, Vibration/*adverse effects
URN: urn:nbn:se:umu:diva-12677DOI: doi:10.1016/j.jhsb.2004.05.004PubMedID: 15336744OAI: diva2:152348
Available from: 2008-01-10 Created: 2008-01-10 Last updated: 2009-12-29Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full textPubMed

Search in DiVA

By author/editor
Lundström, RonnieThornell, Lars-Eric
By organisation
Occupational and Enviromental MedicineAnatomy

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 15 hits
ReferencesLink to record
Permanent link

Direct link