A fluorinated selenide linker for solid-phase synthesis of n-pentenyl glycosides
2004 (English)In: Organic Letters, ISSN 1523-7060, E-ISSN 1523-7052, Vol. 6, no 26, 4885-4888 p.Article in journal (Refereed) Published
A fluorine-labeled selenide linker for installing terminal isolated olefins has been synthesized in high overall yield. The resin-bound linker could be glycosylated both with glycosyl trichloroacetimidates and glycosyl fluorides. The linker did not decompose after oxidation with tBuOOH but underwent beta-elimination when it was subjected to heat. This allowed the released n-pentenyl glycoside 15 to be isolated in excellent yield and purity after filtration.
Place, publisher, year, edition, pages
American Chemical Society (ACS), 2004. Vol. 6, no 26, 4885-4888 p.
IdentifiersURN: urn:nbn:se:umu:diva-14080DOI: 10.1021/ol048053zOAI: oai:DiVA.org:umu-14080DiVA: diva2:153751