Favourable trends in the incidence and outcome ofmyocardial infarction in nondiabetic, but not in diabetic, subjects: findings from the MONICA myocardial infarctionregistry in northern Sweden in 1989–2000
2005 (English)In: Journal of Internal Medicine, ISSN 0954-6820, E-ISSN 1365-2796, Vol. 258, no 4, 369-377 p.Article in journal (Refereed) Published
Background: The aim of this study was to comparetime trends in incidence, case fatality and mortalitydue to myocardial infarction (MI) in patients with orwithout diabetes.Methods: This study was based on the Northe rnSweden MONICA Project MI registry with a targetpopulation of about 200 000 inhabitants in the agegroup 35–64 years in the two northernmostcounties of Sweden. During 1989–2000, 6254patients who had had an MI according to MONICAcriteria were included in this study: 4569 patientshad a first MI and 1685 had a recurrent MI. Sixteenper cent of the men and 20% of the women had haddiabetes mellitus diagnosed prior the MI.Results: Over the 12-year period, there was adeclining trend in incidence and case fatality infirst MI. Also, the event rates (first ever andrecurrent MI) decline d in men without diabetes. Inwomen without diabetes favourable time trendswere seen in first ever MI, recurrent MI and in casefatality. There were no favourable time trends forany of these outcomes in patients with diabetes.Conclusion: In nondiabetic subjects belo w the age of65, the inc idence of, and case-fatality in, MIdeclined. This led to a decreased mortality over the12-year period. These favourable trends over timewere not observed in diabetic subjects.Keywords: acute myocardial infarction, diabetesmellitus, incidence, mortali ty, time trends
Place, publisher, year, edition, pages
2005. Vol. 258, no 4, 369-377 p.
Adult, Case-Control Studies, Diabetic Angiopathies/*epidemiology/mortality, Female, Health Surveys, Humans, Incidence, Male, Middle Aged, Myocardial Infarction/*epidemiology/mortality, Recurrence, Registries, Sweden/epidemiology, Time, Treatment Outcome
Public Health, Global Health, Social Medicine and Epidemiology
IdentifiersURN: urn:nbn:se:umu:diva-15010DOI: 10.1111/j.1365-2796.2005.01552.xISI: 000231825500008PubMedID: 16164577OAI: oai:DiVA.org:umu-15010DiVA: diva2:154682