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Residues determining the binding specificity of uncompetitive inhibitors to tissue-nonspecific alkaline phosphatase.
Umeå University, Faculty of Medicine, Medical Biosciences, Medical and Clinical Genetics.
Umeå University, Faculty of Medicine, Medical Biochemistry and Biophsyics.
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2004 (English)In: Journal of bone and mineral research, ISSN 0884-0431, Vol. 19, no 11, 1862-72 p.Article in journal (Refereed) Published
Place, publisher, year, edition, pages
2004. Vol. 19, no 11, 1862-72 p.
Keyword [en]
Alkaline Phosphatase/*chemistry/genetics/metabolism, Animals, Binding Sites, Binding; Competitive, Bone and Bones/physiology, Drug Design, Enzyme Inhibitors/pharmacology, Homoarginine/pharmacology, Humans, Kinetics, Levamisole/pharmacology, Mice, Mice; Transgenic, Models; Chemical, Models; Molecular, Models; Theoretical, Mutagenesis, Mutagenesis; Site-Directed, Mutation, Phenylalanine/pharmacology, Placenta/enzymology, Protein Binding, Protein Isoforms, Software, Theophylline/pharmacology
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URN: urn:nbn:se:umu:diva-15209DOI: doi:10.1359/JBMR.040608PubMedID: 15476587OAI: oai:DiVA.org:umu-15209DiVA: diva2:154881
Available from: 2008-01-11 Created: 2008-01-11 Last updated: 2011-01-12Bibliographically approved

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