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Sustained osteomalacia of long bones despite major improvement in other hypophosphatasia-related mineral deficits in tissue nonspecific alkaline phosphatase/nucleotide pyrophosphatase phosphodiesterase 1 double-deficient mice.
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2005 (English)In: The American journal of pathology, ISSN 0002-9440, Vol. 166, no 6, 1711-20 p.Article in journal (Refereed) Published
Place, publisher, year, edition, pages
2005. Vol. 166, no 6, 1711-20 p.
Keyword [en]
Alkaline Phosphatase/*deficiency, Animals, Blotting; Western, Calcification; Physiologic/*physiology, Disease Models; Animal, Femur/physiopathology/ultrastructure, Hypophosphatasia/complications/*physiopathology, Immunohistochemistry, Leg Bones/*physiopathology/ultrastructure, Mice, Mice; Knockout, Osteoblasts/metabolism, Osteomalacia/etiology/*physiopathology, Phosphoric Diester Hydrolases/*deficiency, Pyrophosphatases/*deficiency, Skull/pathology, Spectroscopy; Fourier Transform Infrared, Tibia/physiopathology/ultrastructure, Tomography; X-Ray Computed
URN: urn:nbn:se:umu:diva-15265PubMedID: 15920156OAI: diva2:154937
Available from: 2008-01-08 Created: 2008-01-08 Last updated: 2011-01-12Bibliographically approved

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