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Pencil kernel correction and residual error estimation for quality-index-based dose calculations
Umeå University, Faculty of Medicine, Department of Radiation Sciences, Radiation Physics.
Umeå University, Faculty of Medicine, Department of Radiation Sciences, Radiation Physics.
Umeå University, Faculty of Medicine, Department of Radiation Sciences, Radiation Physics.
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2006 (English)In: Physics in Medicine and Biology, ISSN 0031-9155, E-ISSN 1361-6560, Vol. 51, no 23, 6245-6262 p.Article in journal (Refereed) Published
Abstract [en]

Experimental data from 593 photon beams were used to quantify the errors in dose calculations using a previously published pencil kernel model. A correction of the kernel was derived in order to remove the observed systematic errors. The remaining residual error for individual beams was modelled through uncertainty associated with the kernel model. The methods were tested against an independent set of measurements. No significant systematic error was observed in the calculations using the derived correction of the kernel and the remaining random errors were found to be adequately predicted by the proposed method.

Place, publisher, year, edition, pages
2006. Vol. 51, no 23, 6245-6262 p.
URN: urn:nbn:se:umu:diva-15748DOI: 10.1088/0031-9155/51/23/021PubMedID: 17110783OAI: diva2:155420
Available from: 2007-02-27 Created: 2007-02-27 Last updated: 2011-03-25Bibliographically approved
In thesis
1. Verification of dose calculations in radiotherapy
Open this publication in new window or tab >>Verification of dose calculations in radiotherapy
2008 (English)Doctoral thesis, comprehensive summary (Other academic)
Abstract [en]

External radiotherapy is a common treatment technique for cancer. It has been shown that radiation therapy is a both clinically and economically effective treatment for many types of cancer, even though the equipment is expensive. The technology is in constant evolution and more and more sophisticated and complex techniques are introduced. One of the main tasks for physicists at a radiotherapy department is quality control, i.e. making sure that the treatments are delivered in accordance with the dosimetric intentions. Over dosage of radiation can lead to severe side effects, while under dosage reduces the probability for patient cure.

The present thesis is mainly focused on the verification of the calculated dose. Requirements for independent dose calculation software are identified and the procedures using such software are described. In the publications included in the thesis an algorithm specially developed for verification of dose calculations is described and tested. The calculation uncertainties connected with the described algorithm are investigated and modeled. A brief analysis of the quality assurance procedures available and used in external radiotherapy is also included in the thesis.

The main conclusion of the thesis is that independent verification of the dose calculations is feasible in an efficient and cost effective quality control system. The independent calculations do not only serve as a protection against accidents, but can also be the basis for comparisons of the dose calculation performance at different clinics.

Place, publisher, year, edition, pages
Umeå: Strålningsvetenskaper, 2008. 63 p.
Umeå University medical dissertations, ISSN 0346-6612 ; 1224
radiotherapy, dose calculation, quality control, pencil kernel
National Category
Radiology, Nuclear Medicine and Medical Imaging
urn:nbn:se:umu:diva-1931 (URN)978‐91‐7264‐679‐7 (ISBN)
Public defence
2008-12-12, 244, By 7, Norrlands universitetssjukhus, Umeå, 09:00 (English)
Available from: 2008-11-24 Created: 2008-11-24 Last updated: 2012-04-02Bibliographically approved

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Nyholm, TufveOlofsson, JörgenAhnesjö, AndersKarlsson, Mikael
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