Reaction of pyridine N-oxides with Grignard reagents: a stereodefined synthesis of substituted dienal oximes
2007 (English)In: Tetrahedron Letters, Vol. 48, 6941-4 p.Article in journal (Refereed) Published
Rapid addition of Grignard reagents to pyridine N-oxides under mild conditions gave stereodefined dienal oximes in good to excellent yields. This reaction provides an efficient access to substituted olefins with defined stereochemistry that are potentially of interest as bioactives themselves or as versatile synthetic intermediates.
Place, publisher, year, edition, pages
2007. Vol. 48, 6941-4 p.
IdentifiersURN: urn:nbn:se:umu:diva-16188DOI: doi:10.1016/j.tetlet.2007.07.161OAI: oai:DiVA.org:umu-16188DiVA: diva2:155861
Available online 28 July 20072007-08-302007-08-302010-01-08Bibliographically approved