Change search
ReferencesLink to record
Permanent link

Direct link
Fatigue before and after mild traumatic brain injury: Pre-post-injury comparisons in relation to Apolipoprotein E
Umeå University, Faculty of Social Sciences, Department of Psychology.
Department of Psychology, Stockholm University.
Depatrment of Molecular Genetics, Flanders Interuniversity Institute for Biotechnology, University of Antwerp, Belgium.
Umeå University, Faculty of Medicine, Department of Clinical Sciences, Psychiatry.
Show others and affiliations
2007 (English)In: Brain Injury, ISSN 0269-9052, E-ISSN 1362-301x, Vol. 21, no 10, 1049-1054 p.Article in journal (Refereed) Published
Abstract [en]

Primary objective: To assess the incidence of fatigue for persons following a mild traumatic brain injury (MTBI) and to evaluate the relationship between fatigue and APOE genotype. As fatigue is often found to be influenced by anxiety, depression and sleep disturbance, these factors were also measured. Methods and procedures: Thirty-one persons who sustained a MTBI were drawn from a population-based longitudinal study. Each person who sustained a MTBI was matched by age, gender, education and APOE genotype with two non-head injury controls. Self-reported pre- and post-injury incidence of fatigue, anxiety, depression and sleep disturbance was compared within-group and between groups. Results: For the MTBI group, incidence of fatigue was almost twice as common post- than pre-injury, whereas there was no corresponding change in a non-injured control group. Within the MTBI-group, post-injury fatigue was particularly common for carriers of the APOE ε4 allele. Conclusions: Fatigue is common sequela after a MTBI and especially pronounced for carriers of the APOE ε4 allele.

Place, publisher, year, edition, pages
London: Taylor & Francis Ltd , 2007. Vol. 21, no 10, 1049-1054 p.
Keyword [en]
Mild head injury, Fatigue, Apoloprotein E, pre-injury
URN: urn:nbn:se:umu:diva-16665DOI: 10.1080/02699050701630367OAI: diva2:156338
Available from: 2008-01-14 Created: 2008-01-14 Last updated: 2011-03-28Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full text

Search in DiVA

By author/editor
Sundström, AnnaAdolfsson, RolfNyberg, Lars
By organisation
Department of PsychologyPsychiatry
In the same journal
Brain Injury

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 92 hits
ReferencesLink to record
Permanent link

Direct link