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A cytokine in the Drosophila stress response.
Umeå University, Faculty of Medicine, Umeå Centre for Molecular Pathogenesis (UCMP) (Faculty of Medicine). (Dan Hultmark)
2003 (English)In: Dev Cell, ISSN 1534-5807, Vol. 5, no 3, 360-1 p.Article in journal (Refereed) Published
Abstract [en]

The fruit fly, Drosophila melanogaster, has become a popular tool for studying immediate reactions to environmental hazards, such as the heat shock and innate immune responses. In mammals, protective responses to infections and other insults are coordinated by a complex network of cytokines that mediate cell-to-cell signaling. By contrast, the corresponding heat shock and innate immune responses in Drosophila have usually been regarded as cell-autonomous processes. However, in this issue of Developmental Cell, show that cytokines do play a role in mediating an acute phase response in this organism.

Place, publisher, year, edition, pages
2003. Vol. 5, no 3, 360-1 p.
Keyword [en]
Animals, Cytokines/*physiology, Drosophila melanogaster/*physiology, Gene Expression Regulation, Heat-Shock Proteins/physiology, Heat-Shock Response/*physiology, Immunity; Natural/*physiology, Signal Transduction/genetics/physiology, Stress/*metabolism
Identifiers
URN: urn:nbn:se:umu:diva-17057PubMedID: 12967553OAI: oai:DiVA.org:umu-17057DiVA: diva2:156730
Available from: 2007-10-28 Created: 2007-10-28 Last updated: 2011-01-13Bibliographically approved

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PubMedhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Retrieve&list_uids=12967553&dopt=Citation

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