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Somatic and germline clone analysis in mutants of the S-adenosylmethionine synthetase encoding gene in Drosophila melanogaster.
Umeå University, Faculty of Science and Technology, Molecular Biology (Faculty of Science and Technology).
Umeå University, Faculty of Science and Technology, Molecular Biology (Faculty of Science and Technology).
1998 (English)In: FEBS Lett, ISSN 0014-5793, Vol. 427, no 1, 119-23 p.Article in journal (Other academic) Published
Abstract [en]

We have analysed the phenotypic consequences of homozygous mutant clones in the S-adenosylmethionine synthetase encoding gene in Drosophila melanogaster. The results suggest that SamS function is required for cell proliferation/growth in embryonic/early larval cells and during development of imaginal disc cells. Homozygous SamS germline clones can, however, develop and give rise to viable heterozygous offspring. This offspring expresses a Minute-like phenotype. We suggest that this phenotype is caused by an obstruction of the polyamine biosynthesis

Place, publisher, year, edition, pages
1998. Vol. 427, no 1, 119-23 p.
Keyword [en]
Animals, Drosophila melanogaster/embryology/enzymology/*genetics, Female, Male, Methionine Adenosyltransferase/*genetics, Phenotype
Identifiers
URN: urn:nbn:se:umu:diva-17170PubMedID: 9613611OAI: oai:DiVA.org:umu-17170DiVA: diva2:156843
Available from: 2007-11-05 Created: 2007-11-05 Last updated: 2011-01-14Bibliographically approved

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