Somatic and germline clone analysis in mutants of the S-adenosylmethionine synthetase encoding gene in Drosophila melanogaster.
1998 (English)In: FEBS Lett, ISSN 0014-5793, Vol. 427, no 1, 119-23 p.Article in journal (Other academic) Published
We have analysed the phenotypic consequences of homozygous mutant clones in the S-adenosylmethionine synthetase encoding gene in Drosophila melanogaster. The results suggest that SamS function is required for cell proliferation/growth in embryonic/early larval cells and during development of imaginal disc cells. Homozygous SamS germline clones can, however, develop and give rise to viable heterozygous offspring. This offspring expresses a Minute-like phenotype. We suggest that this phenotype is caused by an obstruction of the polyamine biosynthesis
Place, publisher, year, edition, pages
1998. Vol. 427, no 1, 119-23 p.
Animals, Drosophila melanogaster/embryology/enzymology/*genetics, Female, Male, Methionine Adenosyltransferase/*genetics, Phenotype
IdentifiersURN: urn:nbn:se:umu:diva-17170PubMedID: 9613611OAI: oai:DiVA.org:umu-17170DiVA: diva2:156843