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Prevalence of atrial fibrillation and reasons for undertreatment with oral anticoagulants
Umeå University, Faculty of Medicine, Department of Public Health and Clinical Medicine.
Umeå University, Faculty of Medicine, Department of Public Health and Clinical Medicine.ORCID iD: 0000-0001-9422-1186
Umeå University, Faculty of Medicine, Department of Public Health and Clinical Medicine. Department of Cardiology, Sundsvall Hospital, 856 43, Sundsvall, Sweden.ORCID iD: 0000-0002-1239-6239
2024 (English)In: Journal of Thrombosis and Thrombolysis, ISSN 0929-5305, E-ISSN 1573-742X, Vol. 57, p. 101-106Article in journal (Refereed) Published
Abstract [en]

Objectives: To investigate the prevalence of atrial fibrillation (AF), the proportion of AF patients not receiving oral anticoagulation (OAC) and reasons for abstaining from OAC treatment.

Methods: A retrospective cross-sectional study of patients aged 18 years or older with an AF diagnosis on June 1st 2020 in Västernorrland County, Sweden. AF diagnosis was retrieved using the ICD10 code I.48, and medical records were reviewed for comorbidities and documented reasons to abstain OAC treatment.

Results: Of 197 274 residents in Västernorrland County, 4.7% (9 304/197 274) had a documented AF diagnosis. Of these, 19% (1 768/9 304) had no OAC treatment, including 4.2% (393/9 304) with no indication, 2.5% (233/9 304) with a questionable and 2.5% (231/9 304) with a documented clear contraindication for OAC. In total 9.8% (911/9 304) were not treated with OAC despite indication and no reasonable documented contraindication, thus 90.8% (8 447/9 304) of all AF-patients were eligible for OAC treatment. Common reasons for abstaining treatment without reasonable contraindication were present sinus rhythm in 13.7% (125/911), perceived not an OAC candidate in 10.6% (97/911) and anemia in the past in 4.3% (39/911).

Conclusions: In the population of Västernorrland County, a very high AF prevalence of 4.7% was found, of which just over 90% would theoretically benefit from OAC treatment. This is higher than previously reported and stresses the importance of stroke prevention in this large patient group.

Place, publisher, year, edition, pages
Springer Nature, 2024. Vol. 57, p. 101-106
Keywords [en]
Atrial fibrillation, Oral anticoagulation, Prevalence
National Category
Cardiology and Cardiovascular Disease Public Health, Global Health and Social Medicine
Identifiers
URN: urn:nbn:se:umu:diva-214615DOI: 10.1007/s11239-023-02890-yISI: 001066559300001PubMedID: 37704908Scopus ID: 2-s2.0-85171163870OAI: oai:DiVA.org:umu-214615DiVA, id: diva2:1800612
Available from: 2023-09-27 Created: 2023-09-27 Last updated: 2025-02-20Bibliographically approved

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Lilja, JohanSjälander, AndersSjälander, Sara

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