Interpersonal Emotion Regulation (IER) in adulthood has been the area of attention in a growing number of studies over the last decade. Despite the normality of emotion regulation in social situations, focus has mainly been on pathology. Motivated by the lack of salutogenic perspectives, this cross-sectional study aims to shed light on associations between IER strategies and Quality of Life (QOL). Also, to explore age-related aspects, a developmental angle was taken. A non-clinical sample (N=73) residing in Sweden was recruited and responded to the self-assessments Interpersonal Emotion Regulation Questionnaire (IERQ) and WHOQOL-BREF. The respondents were divided into two age groups, younger (NY=35) and older (NO=38) adults. Furthermore, participants were divided into groups based on whether or not they were temporarily experiencing special circumstances affecting life quality. Multiple bivariate correlation analysis was performed on IER factors and QOL domains for the whole group and also for the two group conditions. All IER strategies represented in IERQ were positively associated with all domains of QOL in all conditions, although only some of them were significant correlations. The results indicated that Soothing and Social Modeling can be effective IER strategies in terms of psychological well-being. In the age condition, this was only valid for the younger adults. In addition, the findings supported Soothing as an effective strategy for those experiencing special circumstances. Hence, different correlational patterns emerged related to the specific conditions examined, giving support for context-dependency of Interpersonal Emotion Regulation.