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Early career progression in young adults with coeliac disease: a register‐based retrospective cohort study
Umeå University, Faculty of Medicine, Department of Public Health and Clinical Medicine. Center for Clinical Research Dalarna, Uppsala University, Falun, Sweden.ORCID iD: 0009-0004-1535-5901
Umeå University, Faculty of Medicine, Department of Epidemiology and Global Health.ORCID iD: 0000-0002-0457-2175
Umeå University, Faculty of Medicine, Department of Epidemiology and Global Health.ORCID iD: 0000-0001-8944-2558
Umeå University, Faculty of Medicine, Department of Epidemiology and Global Health.ORCID iD: 0000-0002-5517-0803
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2025 (English)In: Acta Paediatrica, ISSN 0803-5253, E-ISSN 1651-2227Article in journal (Refereed) Epub ahead of print
Abstract [en]

Aim: To investigate early career progression and national insurance use in young adults with paediatric coeliac disease.

Methods: We performed a register study of a population born in Sweden between 1976 and 1992. Coeliac disease was diagnosed before 15 years of age. The comparison population was matched 4:1 by sex, region of residence at birth and birth year/month. We analysed education, employment, income, job position and national insurance use (sickness benefits, parental leave benefits and social welfare provision) at 25 and 30 years of age.

Results: We identified 1812 individuals with coeliac disease (6888 comparison population) at 25 years of age and 263 individuals (984 comparison population) at 30 years of age. No statistically significant differences were seen in education, employment, income, job position, use of parental leave benefits or social welfare provision. More individuals with coeliac disease used sickness benefits at age 25 years (OR 1.34 [95% CI 1.12–1.59]).

Conclusion: In this register study, we showed that coeliac disease diagnosed in childhood does not cause disadvantages on career progression on a population level. However, findings suggest that coeliac disease increases the risk for sickness benefit use.

Place, publisher, year, edition, pages
John Wiley & Sons, 2025.
Keywords [en]
career, children, coeliac disease, gluten-free diet, national insurance use
National Category
Gastroenterology and Hepatology
Identifiers
URN: urn:nbn:se:umu:diva-237021DOI: 10.1111/apa.70073ISI: 001455667300001PubMedID: 40150956Scopus ID: 2-s2.0-105001636639OAI: oai:DiVA.org:umu-237021DiVA, id: diva2:1948495
Funder
Region Västerbotten
Note

Funding: The Center for Clinical Research Region Dalarna, Anna Cederberg foundation, Faculty of Medicine Umeå University, National Research Schoolin General Practice, Region Västerbotten and the Swedish Celiac Disease Association supported with funding of the project. Research reported in this publication was supported by the National Institute of Diabetes And Digestive And Kidney Diseases of the National Institutes of Health under Award NumberK23DK119584. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes ofHealth. This study was supported by the ISSCD M-in-M programme. The ISSCD M-in-M programme has been made possible by an unrestricted grant fromTakeda Pharmaceuticals. The Umeå SIMSAM Lab data infrastructure used in this study was developed with support from the Swedish Research Council, the Riksbanken Jubileumsfond and by strategic funds from Umeå University. The work was done independent of the funding source.

Available from: 2025-03-30 Created: 2025-03-30 Last updated: 2025-04-28

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Johansson, KatarinaNorström, FredrikIvarsson, AnneliRichter Sundberg, LindaSjälander, AndersMyléus, Anna

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