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Trends in spasticity-reducing surgery and botulinum toxin treatment for post-stroke spasticity: a register study on 6,258 patients in Sweden, 2010–2021
Department of Orthopedics and Hand Surgery, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.
Umeå University, Faculty of Medicine, Department of Surgical and Perioperative Sciences, Hand Surgery. Umeå University, Faculty of Medicine, Department of Diagnostics and Intervention.
Hand Center Malmö, Atleva Specialist Care, Malmö, Sweden.
Sahlgrenska Osteoporosis Centre, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden.
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2025 (English)In: Journal of Rehabilitation Medicine, ISSN 1650-1977, E-ISSN 1651-2081, Vol. 57, article id adv42684Article in journal (Refereed) Published
Abstract [en]

Spasticity is characterized by increased muscle tone, which can result in pain, contractures, impaired hygiene, and deformities. Stroke is a leading cause of paresis, and nearly 40% of stroke patients will develop spasticity.

Objective: To assess trends in upper and lower extremity spasticity-reducing surgery and botulinum toxin A (BoNT-A) treatment.

Design: A national cohort register study.

Methods: Upper and lower extremity spasticity-reducing surgery and BoNT-A treatment in Swedish stroke patients over a 12-year period was assessed using the National Patient Register.

Results: A total of 6,258 patients were treated during this period; their mean age was 58, and the majority were male. In both upper and lower extremities, tenotomy was the most common surgical procedure, followed by tendon lengthening. The need for BoNT-A injections was significantly reduced after surgery compared with before surgery. The total number of BoNT-A treatments increased during the study period, and ultrasound guidance of injections became more common.

Conclusion: The frequency of BoNT-A treatments was significantly reduced in patients who underwent surgery. Even though no causative association can be established due to the nature of these registry data, this may indicate that surgery reduces the need for further BoNT-A treatments.

Place, publisher, year, edition, pages
MJS Publishing, Medical Journals Sweden AB , 2025. Vol. 57, article id adv42684
Keywords [en]
botulinum toxin, extremity surgery, spasticity, stroke, tendon transfer
National Category
Surgery
Identifiers
URN: urn:nbn:se:umu:diva-237204DOI: 10.2340/jrm.v57.42684Scopus ID: 2-s2.0-105001002042OAI: oai:DiVA.org:umu-237204DiVA, id: diva2:1950346
Funder
Promobilia foundationAvailable from: 2025-04-07 Created: 2025-04-07 Last updated: 2025-04-07Bibliographically approved

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Blaszczyk, Izabela

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