Residual brain infection in murine relapsing fever borreliosis can be successfully treated with ceftriaxone
2008 (English)In: Microbial Pathogenesis, ISSN 0882-4010, E-ISSN 1096-1208, Vol. 44, no 3, 262-264 p.Article in journal (Refereed) Published
Like several other spirochetes, relapsing fever Borrelia can cause persistent infection of the central nervous system (CNS). By treating mice harboring residual Borrelia duttonii brain infection with the bacteriocidal, cell wall inhibiting antibiotic ceftriaxone, bacteria were cleared from the brain. This shows that the residual infection is not latent but actively growing.
Place, publisher, year, edition, pages
Elsevier, 2008. Vol. 44, no 3, 262-264 p.
Latent, Persistent, Ceftriaxone, Antibiotics, CNS infections, Meningitis
Infectious Medicine Microbiology in the medical area
IdentifiersURN: urn:nbn:se:umu:diva-20789DOI: 10.1016/j.micpath.2007.11.002PubMedID: 18083325OAI: oai:DiVA.org:umu-20789DiVA: diva2:209548