Haemolysis index: an estimate of preanalytical quality in primary health care!
2009 (English)In: Clinical Chemistry and Laboratory Medicine, ISSN 1434-6621, Vol. 47, no 8, 940-944 p.Article in journal (Refereed) Published
Background: Haemolysis is usually caused by inadequate specimen collection or preanalytical handling, and is suggested to be a suitable indicator of preanalytical quality. We investigated the prevalence of detectable haemolysis in all routine venous blood samples to identify differences in preanalytical quality. Methods: Haemolysis index (HI) values were obtained from a Vitros 5,1 in the routine clinical chemistry laboratory for samples collected in primary health care centres (PHCs), nursing homes, and a hospital emergency department (ED). Haemolysis was defined as a HI ≥ 15 (detection limit). Results: Samples from the PHC with the highest prevalence of haemolysis were 6.1 times (95% confidence interval (CI) 4.0-9.2) more often haemolysed compared to the centre with the lowest prevalence. Of the samples collected in primary health care, 10.4% were haemolysed compared to 31.1% in the ED (p< 0.001). A notable difference in haemolysed samples was found between the ED section staffed by emergency medicine physicians and the section staffed by primary health care physicians (34.8% vs. 11.3%, p<0.001). Conclusions: The significant variation in haemolysis indices among the investigated units is likely to reflect varying preanalytical conditions. The HI is a valuable tool for estimation and follow-up of preanalytical quality in primary health care.
Place, publisher, year, edition, pages
2009. Vol. 47, no 8, 940-944 p.
blood specimen collection, haemolysis, medical errors, phlebotomy, primary health care, Quslity indicators
IdentifiersURN: urn:nbn:se:umu:diva-21255OAI: oai:DiVA.org:umu-21255DiVA: diva2:211193