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A novel t(2;17) in transformation of essential thrombocythemia to acute myelocytic leukemia.
Umeå University, Faculty of Medicine, Public Health and Clinical Medicine, Medicine.
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2004 (English)In: Cancer Genetics and Cytogenetics, ISSN 2210-7762, E-ISSN 2210-7770, Vol. 148, no 1, 77-9 p.Article in journal (Refereed) Published
Abstract [en]

A transformation of essential thrombocythemia to acute myelocytic leukemia (AML), myelodysplastic syndrome, or agnogenic myelocytic metaplasia is a relatively rare event. It occurs in 1%-4.5% of all patients with either treated or untreated essential thrombocythemia. Cytogenetic changes in the transformation to AML are common. We report the case of a patient treated for essential thrombocythemia with hydroxyurea for 49 months. He developed AML with a t(2;17), which to our knowledge has not been described in the literature.

Place, publisher, year, edition, pages
2004. Vol. 148, no 1, 77-9 p.
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URN: urn:nbn:se:umu:diva-22341PubMedID: 14697645OAI: oai:DiVA.org:umu-22341DiVA: diva2:214567
Available from: 2009-05-06 Created: 2009-05-06 Last updated: 2017-12-13

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