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Low frequency of phlebographic deep vein thrombosis after laparoscopic cholecystectomy: a pilot study
Umeå University, Faculty of Medicine, Department of Surgical and Perioperative Sciences, Surgery.
Umeå University, Faculty of Medicine, Department of Surgical and Perioperative Sciences, Surgery.
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2006 (English)In: Clinical and applied thrombosis/hemostasis, ISSN 1076-0296, E-ISSN 1938-2723, Vol. 12, no 4, 421-426 p.Article in journal (Refereed) Published
Abstract [en]

To investigate the rate of deep vein thrombosis (DVT) after laparoscopic surgery, 50 patients underwent bilateral phlebography 7-11 days after laparoscopic cholecystectomy (LC). All received thromboembolism prophylaxis, either low molecular weight heparin (LMWH) or dextran. Three patients were converted to open cholecystectomy. D-dimer was investigated preoperatively, on day 1 and on the day of phlebography. One asymptomatic DVT was found. One phlebogram was incomplete. Seven phlebograms were not optimal but of sufficient quality to rule out DVT. The frequency of DVT was thus 1 of 49 or 2.0% (95% confidence interval, 0-6.0%). No anticoagulants were prescribed after discharge. No patient developed late thromboembolic complications. D-dimer values increased significantly at day 1 and were further increased at the time of phlebography. The frequency of phlebographical DVTs thus seems to be low despite prophylaxis of questionable efficacy. The D-dimer values, however, suggest that the effects of LC on coagulation/fibrinolysis have a duration of longer than 1 week.

Place, publisher, year, edition, pages
Sage Publications, 2006. Vol. 12, no 4, 421-426 p.
Keyword [en]
thromboembolic complications, deep vein thrombosis, laparoscopic cholecystectomy, phlebography
National Category
Cardiac and Cardiovascular Systems Hematology
Identifiers
URN: urn:nbn:se:umu:diva-22698DOI: 10.1177/1076029606293425ISI: 000240762400003PubMedID: 17000886OAI: oai:DiVA.org:umu-22698DiVA: diva2:217650
Available from: 2009-05-15 Created: 2009-05-15 Last updated: 2017-12-13Bibliographically approved

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